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» Divine Intervention Podcasts

Divine Intervention Episode 451: Serotonin Syndrome (with integrations)

» Divine Intervention Podcasts

Divine-Favour Anene

Medicine, Education, Science & Medicine, Higher Education

4.9929 Ratings

🗓️ 12 April 2023

⏱️ 22 minutes

🧾️ Download transcript

Summary

Serotonin syndrome is very commonly tested on all the USMLE exams. In this podcast, I discuss relevant pathophysiology and make lots of integrations with other disciplines that many should find helpful. Audio Download

Transcript

Click on a timestamp to play from that location

0:00.0

Okay, welcome. My name is Devine. Welcome to episode 451 of the Devine

0:07.8

Intervention Podcast. In to this podcast we're going to be discussing a topic, but before I discuss that topic, I need to give a vignette first.

0:18.0

What if they give you a question about a 25 year old male.

0:24.0

They tell you that he has a history of multiple mental problems,

0:29.0

mental health problems, and you know he has a history of depression and anxiety and he is

0:37.8

currently on pharmacotherapy although he has not seen his primary care physician in a few months.

0:47.0

And then you're told that he comes into the emergency room because for the past few days he has been having

0:56.5

fevers he has been having chest pain he has been feeling short of breath, he has had like some mild weight loss.

1:08.5

And then they tell you that they are track marks on his skin and they tell you that a new member is heard at the left

1:20.2

upper external border. And sorry, at the left lower external border, I think you're told that blood

1:29.2

cultures are obtained and the patient is started on Empiric Antibiotic Therapy.

1:36.0

Now, they didn't tell you that, you know, results of blood cultures show that,

1:42.0

show gram positive coxi that do not respond to vancomysine therapy that are not

1:51.8

susceptible to vancomysine so that the patient is switched to another therapy.

1:56.0

And then you're told that all 24 hours later,

2:01.0

this patient starts becoming more and more febral. So you know they say maybe

2:06.8

when you came into the hospital is temperature of 102 Fahrenheit, but now it's 104 degrees

2:12.0

Fahrenheit 105. They tell you that he has like some

2:16.8

muscle rigidity and they tell you that he has like 4 plus deep tendon reflexes and they tell you that a urine bag has become red.

2:30.0

And they tell you that he has these hyper kinetic movements of his extremities.

2:35.0

And then our friends at the USMLis will then ask,

2:40.0

what is the next best step in in management and they can put Dantral in as an answer

...

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