#452 Learning about Teplizumab
Juicebox Podcast: Type 1 Diabetes
Scott Benner
4.7 • 1.6K Ratings
🗓️ 12 March 2021
⏱️ 62 minutes
🧾️ Download transcript
Summary
Enlightening conversation with Francisco Leon, MD, PhD, and the CSO and co-founder of ProventionBio, the company potentially bringing Teplizumab to market if approved by FDA. Leon is a aSpanish immunologist and self-described “autoimmunity aficionado” focused on eradicating autoimmune disease through early detection and prevention. He clearly and comprehensively explains how autoimmune diseases are similar, research supporting the unexpected link between coxsackie virus and T1D in studies, and research on Teplizumab which has a BLA under review for approval by FDA for patients at risk of T1D with a PDFUFA goal date of July 2021.
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Transcript
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| 0:00.0 | Hello friends and welcome to episode 452 of the Juicebox podcast. |
| 0:05.4 | My guest in this episode is Francisco Leon and you are not going to want to miss a word |
| 0:10.2 | of what he has to say. |
| 0:24.6 | We may recall that recently on episode 433, Carla Greenbaum was on talking about trial |
| 0:30.2 | net and during that conversation she spoke about a drug called, oh, ready here I go, |
| 0:35.3 | to plzimob. |
| 0:36.6 | To plzimob? |
| 0:37.6 | To plzimob. |
| 0:38.6 | I think that's right, to plzimob. |
| 0:40.5 | Well, I might not be able to say it, but you definitely want to hear about it. |
| 0:45.4 | What's going to come next is an hour long conversation that I found absolutely riveting |
| 0:50.6 | as a person who has family members and loved ones impacted by autoimmune disease. |
| 0:56.8 | I hope it strikes you the same way. |
| 1:00.0 | Please remember while you're listening that nothing you hear on the Juicebox podcast |
| 1:03.1 | should be considered advice, medical or otherwise, always consult a physician before making |
| 1:09.2 | any changes to your health care plan or becoming bold with insulin. |
| 1:14.3 | Alright, a little more business and then we'll get right to it. |
| 1:19.0 | Let's let the music do its thing first though. |
| 1:37.4 | Today's episode of the Juicebox podcast is ad free, but that is because of the support |
| 1:43.4 | of Omnipod Dexcom. |
| 1:46.1 | The contour next one, blood glucose meter touched by type 1.org, the T1D exchange and |
| 1:53.0 | GVOC hypopen. |
... |
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