A series of medical mix-ups left one woman dead and her doctor in prison for negligent homicide.

But that wasn't the entire story.

In a single strand of hair, a forensic toxicologist found evidence of another medical mystery,

one that made headlines around the world.

Hi, say Happy Halloween!

Happy Halloween! Who is that guy?

1997 looked like it would be a banner year for the Pignotaro family.

Dr. Anthony Pignotaro had a thriving medical practice, a wife, two children and social standing.

That's great, Ralph.

Dr. Pignotaro was also an entrepreneur.

He invented and wore the snap-on toupee held in place by four bolts drilled into the skull.

He's always been different and he just came up with this idea.

I could say off the top of his head, but...

I remember laughing about it, it was such a lot of many, many, many jokes around the family

and even when he was around. But he was that serious about it.

His medical practice consisted primarily of cosmetic surgery which he performed in his office.

One of his patients was 26-year-old Sarah Smith, a young mother of two scheduled to have breast augmentation.

Dr. Pignotaro had no anesthesiologist or registered nurse present.

His only assistants were his wife and a licensed practical nurse.

Sarah Smith was viewing pain so that Dr. Pignotaro ordered a little more sodium penitle to dull the pain.

When he did that, her system started shutting down and she was losing oxygen.

At that point he broke scrub and I remember him tapping around the chest and calling out her name

...