3 • 2.6K Ratings
🗓️ 30 July 2024
⏱️ 39 minutes
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Gary Gravina, a skilled carpenter and Marine, was rushed to the ER in 2016 due to severe flu-like symptoms which morphed into a brutal battle with a mysterious disease. Discover how Gary's dire condition would lead him to Dr. David Fajgenbaum and Dr. Grant Mitchell, who had become experts on his rare disease. See how their collaboration not only saved Gary’s life but also significantly impacted the field of medicine.
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****** SPOILER ALERT BELOW ******
If you’re looking for information on Castleman disease or if would like to find out more about the work of Grant, David, and the Every Cure team, visit EveryCure.org.
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0:00.0 | Previously, unsyptomatic. |
0:06.0 | David Faganbaum, a college quarterback, deeply impacted by his mother's fight with brain cancer, was a prime example of peak health and motivation. |
0:15.0 | The moment that I saw her dealing with her cancer, I just said, this is what I have to spend the rest of my life doing. |
0:24.1 | And by this, it's taking care of people with horrible diseases and it's searching for |
0:28.3 | treatments so that people don't suffer. |
0:31.5 | But during med school, everything quickly came crashing down when Castleman disease took him from treating patients to the brink of death in a matter of days. |
0:41.6 | I was so sick that my doctors encouraged my family to say goodbye to me. |
0:47.0 | I'll never forget the moment when a priest came in and read him his last rites. |
0:52.2 | I remember I couldn't really keep it together. |
0:55.6 | I couldn't hide how horrifying it was to see him in that state. |
1:01.6 | After exhausting all the treatments available for Castleman, |
1:05.5 | David's body was ravaged by chemo and he was out of viable options. |
1:09.9 | That's when he decided to take matters into his own |
1:12.3 | hands. I had to take some action, and it had to be a pretty crazy step, and that is to start |
1:18.4 | testing one of these drugs that I was studying in the lab on myself. All the drugs I was studying |
1:23.2 | in the lab were all FDA-approved for something else. they just weren't used for Castleman. |
1:28.3 | After repurposing a medicine originally designed for kidney transplant patients to send his |
1:33.8 | disease into long-term remission, David was determined to prevent others from that similar |
1:39.0 | dead end. His theories around expanding the approved uses for certain medicines would quickly be put to the test seeing Gary Gravina fight for his life against Castleman, just like David had a few short years before. |
1:54.5 | Yes, his heart is technically beating. Yes, he's technically breathing because of what we're doing medically. |
2:00.0 | But he's not going to come back from this. |
2:02.1 | And I just remember being so devastated to hear that. |
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