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DIP Ep 596: 2025 USMLE Step 1 Free 120 Discussion Part 11b (Q106-110, super helpful for Step 2 and 3!)

» Divine Intervention Podcasts

Divine-Favour Anene

Medicine, Education, Science & Medicine, Higher Education

4.9929 Ratings

🗓️ 25 April 2025

⏱️ 26 minutes

🧾️ Download transcript

Summary

In this podcast, I continue the Step 1 Free 120 discussion. I discuss a lot of items relating to hematology, infectious diseases, and cardiology. Series 12 to follow shortly for the conclusion of the series. Email me through the website if you’re interested in my Step 1-3 classes. Audio Download

Transcript

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0:00.0

All right, welcome. This is episode 596 of the Divine Intervention podcast. In today's podcast,

0:07.1

we're going to be continuing the Step 13-120 series. This is going to be series 11B. Again,

0:14.7

God willing, series 12 will be the last. So here we're going to deal with, again, I want to do them in fives or tens.

0:22.3

So I'm going to do 106 to 110 here. And then, God willing, in probably in the next episode, we're just going to finish

0:28.5

up the remaining questions. All right. So question 106. I think the last podcast was kind of long

0:34.3

because 101 to 105 just had a lot of pretty high-year-old things to

0:37.6

discuss.

0:38.6

So question 10-year-old boy is brought to the physician because of a three-week history

0:44.0

of nosebleeds and easy bruiseability.

0:47.1

His older brother has had similar episodes.

0:50.0

He is at the 30th percentile for height and weight.

0:53.5

Fiscal examination shows nasal and ginger- bleeding and several echinoses over the trunk

0:58.2

and upper and lower extremities in various stages of healing.

1:03.3

Lap studies show a platelet count of 300,000, which is normal.

1:07.3

Platelet adhesion testing shows a normal response to ristocetin, but aggregation does not

1:12.9

occur in response to thrombin.

1:15.6

Platelet morphology is normal.

1:17.5

Prothrombing time and activated partial thromboplastin timer within the reference ranges.

1:23.3

A defect in which of the following is the most likely cause of the findings in this patient.

1:29.1

This is a very simple question if you understand primary hemostasis.

1:33.5

Remember, primary hemostasis has a bunch of steps, right?

1:36.3

So the very first step is the adhesion step where GP1B binds to von Willybran factor.

...

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