4.9 • 929 Ratings
🗓️ 25 April 2025
⏱️ 26 minutes
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0:00.0 | All right, welcome. This is episode 596 of the Divine Intervention podcast. In today's podcast, |
0:07.1 | we're going to be continuing the Step 13-120 series. This is going to be series 11B. Again, |
0:14.7 | God willing, series 12 will be the last. So here we're going to deal with, again, I want to do them in fives or tens. |
0:22.3 | So I'm going to do 106 to 110 here. And then, God willing, in probably in the next episode, we're just going to finish |
0:28.5 | up the remaining questions. All right. So question 106. I think the last podcast was kind of long |
0:34.3 | because 101 to 105 just had a lot of pretty high-year-old things to |
0:37.6 | discuss. |
0:38.6 | So question 10-year-old boy is brought to the physician because of a three-week history |
0:44.0 | of nosebleeds and easy bruiseability. |
0:47.1 | His older brother has had similar episodes. |
0:50.0 | He is at the 30th percentile for height and weight. |
0:53.5 | Fiscal examination shows nasal and ginger- bleeding and several echinoses over the trunk |
0:58.2 | and upper and lower extremities in various stages of healing. |
1:03.3 | Lap studies show a platelet count of 300,000, which is normal. |
1:07.3 | Platelet adhesion testing shows a normal response to ristocetin, but aggregation does not |
1:12.9 | occur in response to thrombin. |
1:15.6 | Platelet morphology is normal. |
1:17.5 | Prothrombing time and activated partial thromboplastin timer within the reference ranges. |
1:23.3 | A defect in which of the following is the most likely cause of the findings in this patient. |
1:29.1 | This is a very simple question if you understand primary hemostasis. |
1:33.5 | Remember, primary hemostasis has a bunch of steps, right? |
1:36.3 | So the very first step is the adhesion step where GP1B binds to von Willybran factor. |
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