Welcome back to the real-life pharmacology podcast.

Hope you're enjoying the first few episodes there.

We're up to number 18, I believe, here.

And with this episode, I'm going to cover dopamine agonis.

Okay, so this class of medication is typically referred to as Parkinson's medication or an anti-parkinson's type agent.

And the two classic medications that I always see used in clinical practice is pramapixel, which the brand name for that is Myrapex, Enropineral.

Brand name is Requip.

Now, again, dopamine agonist,

so this is going to stimulate dopamine receptors in the central nervous system,

and in giving that dopamine stimulation,

that can help manage Parkinson's. So with that said, I've talked about the antipsychotics

before in their role as being a dopamine antagonist.

So if you remember these agents,

the prima peypaxil and the ripineral,

these are going to be dopamine agonists,

so the opposite of antipsychotic type medications as far as their mechanism of action goes.

So hopefully that can allow you to remember that these medications can be used for

Parkinson's. In clinical practice, however, most often I see these medications used for restless leg syndrome.

So a very important distinction to remember there.

Memorable side effects from these medications.

Orthostasis can happen.

Rarely I've seen edema happen or kind of swelling around the ankles.

...