Hello, and welcome back to Atcrack. I'm Jed Woltbaugh, and I'm really excited to have with me today a really fantastic guest all the way from Denmark, who is really just a world expert on hypoxia and listeners will know it is a topic near and dear to my heart.

We're going to talk about two recent studies articles that Dr. Mayhoff published, and in fact that is my guest Christian Mayhoff, who as many of you will know is just a prolific researcher when it comes to many things including hypoxia.

He's the head of research and an associate research professor in the Department of anesthesia and intensive care in Copenhagen University Hospital in Copenhagen, Denmark, and he's coming to us all the way from there.

They are really exciting to have him. As I said, he's got two trials. One, the Vixie trial that was published in anesthesiology recently that looked at, and we'll talk about the details, but that looked at hypoxia in the operating room, and then a second coming out or that just recently came out in A&A that looked at some data retrospectively, and we'll talk about how the findings of those two articles are actually quite different quickly before we jump in.

And remember, you can get CME if you need it by going to ackrack.com and clicking on the link in the show notes. That fantastic CME opportunity is provided by CMEFI, so go check it out if you need some CME.

And now, Dr. Christian Mayhoff, thanks so much for coming on the show.

Thank you again. Thank you very much for being part of the show. I really look forward to it, and then have you also see oxygen use in anesthesia and intensive care?

Yeah, it's a important aspect of your interest. I definitely share that, and I've been working for a bit for the last 15 years or more.

Fantastic. Well, thank you for the work you've done, and that you continue to do. Let's start just with you. Tell the audience a little about you, as you said, you know, what you do now, what your day to day is, and how you got where you are.

Thank you. Yeah, so today, I'm head of research at the Department of Nutrition and intensive care, basically a hospital, that's the general hospital for the Copenhagen area.

And apart from my research time, which is always full time, just more than I do on calls and work daily at both the operation room and the ICU.

So the then you share a way of being an astrologist specialist, actually both take care of the ICU patient as well as doing an institution, or we have a lot of emergency medical conditions and a lot of patients with a particle memory.

The conditions undergoing, rather a lot of surgery, and that's why I find it very important to care for these patients and reduce the frequency of how to get full memory on the patients.

Fantastic. And, you know, just like you're asking, let me ask you, is it true that in a lot of Europe and potentially in Denmark too, are all anesthesiologists basically also do intensive care, it's kind of one in the same, or you don't do do a separate training for intensive care, or it's just all part of the same training.

The specialty is combined and during specialty training, you go to both the YOA and the ICU.

So I found that as a great advantage because some of the intensive care treatment of patients and improving their organ function, that is very relevant being in the YOA or for difficult cases to optimize the patient and care for them.

And also likewise being specialist in general anesthesia, some advantages in the ICU. So that's all. And then, of course, after specialty training, that we will subspecialize in each subspecialty.

But we have the same conference in the morning and she and her own goal.

Okay, so there is additional like a fellowship in critical care for those who want to really specialize in it.

Okay, okay. And are the ICUs in Denmark mostly staffed with anesthesiologists, or are there also, you know, medical trained like pulmonary critical care through a medicine residency?

Do they work in ICUs there as well?

The ICUs are, in fact, a little different from the North American way of having ICUs.

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