It was good news and bad news for the 49ers as they departed for Buffalo on Friday.

Quarterback Brock Purdy will be back in the starting lineup, but six other 49ers

starters were ruled out of action due to injuries.

So let's talk Turkey on this episode of 49ers talk with general

manager John Lynch. He stops by to field questions about the current season. Where have things

gone wrong and who are some of the building blocks the team has identified for the future?

But first, Jennifer Lee Chan and I will bring you up to date on the 49ers current injury situation

and who will step into the lineup Sunday night against the Buffalo Bills.

We'll have all that and much more on this episode of 49ers talk coming at you right now.

Welcome to another episode of 49ers talk on NBC Sports Bay Area.com. Introducing your hosts, Matt Mayoko and

Jennifer Lee Chan. All right, this is 49ers talk, brought to you by your locally owned

Big O Tires, the team you trust. And Jennifer, as we get prepared to head to Buffalo, we are

potentially going to see a lot of snow.

And we definitely know we're going to see a lot of guys who aren't usually starters in starting roles Sunday when the fairs meet the bills on Sunday night football.

Yeah, but there are a few that we are used to seeing, and that's Brock Purdy, he's going

to make his return in Buffalo.

I like how Kyle Shanahan said, Kyle Shanahan said, you know, a lot can happen.

He didn't revert to the, we all could be dead by Sunday, but he said a lot of things

could happen before Sunday, but as of right now on Friday,

when he gave the press conference, Brock Purdy is playing. Yeah, he said that he wouldn't be playing

if he's healthy and that he's playing. So it was about as certain as I thought he could, you know,

I didn't think he'd be actually that certain. I thought it'd be, you know, he's listed as questionable,

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