Neurologist Sounds the Alarm: Silent Symptoms of Dementia & Brain Decline with Dr. David Perlmutter

Dhru Purohit Show

Dhru Purohit

Medicine, Health & Fitness, Alternative Health

4.7 • 3.4K Ratings

🗓️ 13 March 2024

⏱️ 97 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

This episode is brought to you by Birch Living and Bioptimizers.

According to today’s guest, the seeds of Alzheimer’s are planted at least twenty years before a diagnosis. So, it’s never too early to think about the lifestyle changes that can influence brain health and the risk of developing neurodegenerative diseases. Dr. David Perlmutter shows us what we can do to protect our brain health and lower our risk.

Today on The Dhru Purohit Show, Dhru sits down with Dr. David Perlmutter to discuss research around the top four factors that can determine the risk of developing Alzheimer’s and his lifestyle tips on prevention. Dr. Perlmutter shares the tools we can use to analyze our brain’s use of energy and discusses the importance of engaging in physically and mentally stimulating activities. He also shares his hot takes on the community’s top questions and reiterates the importance of changing our minds and keeping up with the latest research.

Dr. David Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain, among other books, and his most recent book, Drop Acid. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease and has published extensively in peer-reviewed scientific journals, including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition.

In this episode, Dhru and Dr. Perlmutter dive into (audio version / Apple Subscriber version):

Early warning signs of Alzheimer’s and dementia (00:00:40 / 00:00:40)
Influences you can have over your lifestyle (6:50 / 5:44)
4 factors that determine our risk of Alzheimer’s (12:28 / 11:00)
The role of oral microbiome in our brain health (28:41 / 25:31)
Tools to analyze our brain’s use of energy (31:49 / 28:46)
The risks of a sedentary lifestyle on brain health (34:06 / 30:55)
The importance of engaging in mentally and physically stimulating activities (49:10 / 45:30)
Sleep as a powerful pillar in Alzheimer's prevention (52:30 / 49:35)
Key supplements for brain health (58:46 / 55:40)
Future therapeutics that could help Alzheimer’s patients (1:20:10 / 1:17:20)
Dr. Perlmutter’s hot takes on community questions (1:23:13 / 1:20:10)

Also mentioned in this episode:

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Transcript

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0:00.0	Dr. David Perlmutter, today we're talking all things dementia, Alzheimer's, and neurodegenerative diseases.
0:07.0	How to catch them early so we can prevent them from developing in the first place.
0:12.0	You know, one of the mind-blowing things
0:14.4	that many people, including myself,
0:16.0	have learned from your work is that these diseases,
0:19.7	like Alzheimer's and dementia,
0:21.4	are not something that we one day just wake up with that all of a sudden we're okay and then one day we're not in fact for the vast majority of people their diagnosis was years and often decades in the making.
0:35.0	So I'd love to start there.
0:36.7	What are some of the earliest warning signs, well before these diseases develop,
0:42.4	that someone is on their way to developing them.
0:46.2	Let me first say that your risk of becoming
0:48.9	an Alzheimer's individual if you reach 85 years of age is 50-50.
0:54.3	So we're talking about an awful lot of people.
0:57.2	And for younger people who want to know,
0:59.4	are there issues that might be indicative of increased risk at this stage of my life when I'm 30, when I'm 40, there are.
1:06.6	And these are actually very straightforward metrics and they can be determined with, for example, a tape measure around your belly or your blood
1:14.1	sugar or your blood pressure or your level of physical activity. With those
1:18.1	four issues being brought into line I'll just step out here and indicate that you might be able to reduce your risk of
1:24.5	Alzheimer's by around 70%. Wow. Yeah. And what you said actually is true and
1:30.2	really important and that is that the seeds of Alzheimer's are soon 20 to 30 years prior to the
1:38.9	clinical manifestations. The clinical manifestations being things like failing memory, poor judgment, difficulties with what we call executive function, putting together complex ideas to carry out an activity.
1:51.0	We can actually determine that early on and predict who is going to end
	...

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