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What Next | Daily News and Analysis

TBD | This Is Your Brain On Ketamine

What Next | Daily News and Analysis

Slate

News, Daily News, News Commentary, Politics

4.6 • 2.3K Ratings

🗓️ 30 March 2025

⏱️ 28 minutes

🧾️ Download transcript

Summary

Ketamine has gone from a recreational psychedelic to an approved treatment, and it has caught on in Silicon Valley in a big way. Are the long-term effects of using ketamine—recreationally or therapeutically—sufficiently known? Are we witnessing them right now? Guest: Shayla Love, staff writer for the Atlantic. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

So, you want to be a marketer. It's easy. You just have to score a ton of leads and figure out a way to turn them all into customers.

0:08.0

Plus manage a dozen channels, write a million blogs and launch 100 campaigns all at once.

0:12.5

When that's done, simply make your socials go viral and bring in record profits.

0:16.7

No sweat. Okay, fine. It's a lot of sweat.

0:20.5

But with HubSpot's AI-powered marketing tools,

0:23.2

launching benchmark-breaking campaigns is easier than ever.

0:26.7

Get started at HubSpot.com slash marketers.

0:34.9

When I got Shayla Love on the line,

0:37.0

I wanted her to describe in detail how ketamine can make you feel.

0:42.2

And this comes from interviewing lots and lots of people who have taken it both for trying to treat depression symptoms and also for fun and taking it at raves and dance parties.

0:52.2

Shaila's a science journalist, and she's done a lot of reporting on ketamine.

0:56.0

She wrote a great story in the Atlantic about ketamine's effects on the human brain.

1:01.0

It's called it dissociative, and the reason it's called that is it can make you feel sort of detached from your body.

1:08.0

So sometimes that means your limbs feel really big, sometimes it means your body sort of floats away from you, you float away from your body. So sometimes that means your limbs feel really big. Sometimes it means your body sort of

1:12.5

floats away from you. You float away from your body. It can also lead to feelings of like

1:16.7

euphoria. Your thoughts can feel really special and magical. And at lower doses, it can be a little bit

1:23.8

like being tipsy or being drunk.

1:30.8

It's a really effective anesthetic.

1:36.3

A few years ago, I was in the emergency room, and a teenage kid next to me had dislocated his thumb playing basketball.

1:38.3

He got a ketamine dose before the doctors maneuvered his thumb back into its socket.

1:44.1

The reason that people take it in the hospital is that it's FDA approved as an anesthetic.

1:48.4

So if you take it a really high dose, you will lose consciousness.

...

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