📌 Sponsors To Check Out: 🛌 For Black Friday code "MPMD" will save $400 off the Pod 4 Ultra, or $600 off the complete bundle: https://www.eightsleep.com/moreplatesmoredates/ ⚕️ Marek Health - Preventive Medicine, HRT, & Rigorous Blood Work: https://bit.ly/373k791 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ———————————— 🕑 Timestamps: 0:00:00 - 0:13:37 – Epigenetics, Methylation, And Aging 0:13:37 - 0:19:02 – Books That Have Dramatically Impacted Peter’s Life. His Current Career Goals. 0:19:02 - 0:22:42 – Sponsor: Eight Sleep (The Most Impactful Sleep Enhancing Device I Have Ever Used) 0:22:44 - 0:29:50 – AI, And Why Peter Typically Doesn’t Find Tests That Look For Early ASCVD Valuable 0:29:50 - 0:32:12 – Is There An APOB Level That Guarantees No Risk Of Atherosclerosis? 0:32:12 - 0:33:27 – For Those With Hypofunctioning PCSK9 And Extremely Low LDL-C, What Is Their Average Age Of Death, And What Are They Dying From? 0:33:27 - 0:35:06 – How Much Cholesterol Is Needed For Brain Development? 0:35:06 - 0:36:22 – How Lipid Managing Medications Work 0:36:22 - 0:41:16 – How Peter Evaluates The Best Strategy For Managing APOB For Each Patient 0:41:16 - 0:42:39 – Can You Trust Grocery Store Olive Oil? 0:42:39 - 0:44:09 – Is Olive Oil Healthier Than Eating Less? 0:44:09 - 0:47:56 – If You’re Thriving With Bad Lipids, What Should You Do? 0:47:56 - 0:49:34 – Are Statins Evil? 0:49:34 - 0:53:00 – Tests For Targeted Lipid Management 0:53:00 - 0:56:28 – Bempedoic Acid Vs. Statins 0:56:28 - 1:00:03 – Peter’s Multipronged Approach To Lipid Managing Pharmacology 1:00:03 - 1:05:22 – Sponsor: Marek Health (Preventive Medicine, HRT, & Rigorous Blood Work) 1:05:22 - 1:06:45 – Liver Toxicity And NAFLD 1:06:45 - 1:08:57 – Which Statins Are The Most Likely To Cause Side Effects? 1:08:57 - 1:10:49 – Repatha 1:10:49 - 1:14:04 – Will Obicetrapib Obliterate Atherosclerosis? 1:14:04 - 1:17:47 – Medications That Lower Lp(a) 1:17:47 - 1:25:01 – If Someone Has High Lp(a), But Excellent Metabolic Health, Can They Still Develop Premature Heart Disease? 1:25:01 - 1:26:50 – The Reason Why We Develop Plaque In Arteries, But Not Veins 1:26:50 - 1:27:33 – Maintain ≤ 120/80 Blood Pressure To Smash Your Risk Of Heart Disease And Dementia 1:27:33 - 1:28:34 – Is Lower Than 120/80 Better? 1:28:34 - 1:31:49 – How To Fix High Blood Pressure 1:31:49 - 1:34:12 – DEXA Scans And What A “Good” FFMI Is 1:34:12 - 1:36:24 – Is There Any Way To Verify Endothelial Damage? 1:36:24 - 1:38:16 – How Helpful Is A CT Angiogram? 1:38:16 - 1:40:06 – Can You Accurately Detect Plaque Accumulation In Yearly Intervals With CT Angiography? 1:40:06 - 1:43:47 – Why You Can Have No Detectable Inflammation In Bloodwork, But Still Develop Raging Atherosclerosis 1:43:47 - 1:51:24 – Why Peter Is Starting HRT, And What His Protocol Will Be 1:51:24 - 2:00:47 – Women’s Birth Control Options 2:00:47 - 2:05:42 – When Should Women Start HRT? 2:05:42 - 2:15:48 – Optimizing Women’s HRT Protocols 2:15:48 - 2:18:51 – The Prevalence Of Hypothyroidism 2:18:51 - 2:22:09 – When Should You Treat Inflammation With Supplements Or Medications? 2:22:09 - 2:24:48 – Will Cold Plunge Pre-Workout Inhibit Muscle Growth? 2:24:48 - 2:25:43 – Cold Plunge Increases Dopamine As Much As Coke!? 2:25:43 - 2:30:54 – Peter’s Use Of Modafinil, Nicotine, Caffeine, And What He Thinks The Best Nootropic Is 2:30:54 - 2:33:29 – How To Properly Dose Omega-3 Supplements 2:33:29 - 2:38:30 – Sponsor: Gorilla Mind (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) 2:38:30 - 2:42:33 – What Actually Causes Brain Fog? 2:42:33 - 2:46:36 – How Obesity Impacts Mitochondrial Function 2:46:36 - 2:48:38 – Ideal Daily Magnesium Intake 2:48:38 - 2:51:42 – What Are The Most Important Sleep Metrics? 2:51:42 - 3:22:27 – F1 Talk 3:22:27 - 3:30:26 – Reconnecting Peter Attia With His Long-Lost Obsession... Tearing Phone Books! ————————————