So, guys, Derek, moreplacemorelydes.com. Today we're going to be talking about this study.

Some of you guys tag me in on Instagram called muscle androgen receptor content, but not systemic

hormones is associated with resistance training induced skeletal muscle hypertrophy and healthy young men.

So I'm nearly positive.

We went over the study before during my, I don't know, one of my mechanism of action videos

in terms of talking about androgens and AR activation and what happens subsequent to that.

And as well as my carnitine video, because that was talking directly about how you would hypothetically

upregulate AR content to get a greater bang for your buck out of your anabolic.

So in this study, basically the abstract outlines, like I would highly, I would recommend you actually read it if you want to learn exactly how this stuff works.

But in general, basically it outlines how actual hormone concentrations in the

serum are not necessarily indicative of what is going to equate to how much muscle you build so

if you see a guy with a 700 nanogram per decilator total test level well not only does his free

actually be the one that's not bound to shBG and albumin and is kind of circulating

around to do what it needs to do at the androgen receptor. But not only that, which is what most

people think is the end-all be-all if you're going to build muscle or not, is how much is your

free testosterone level? But what this outlines is it comes down to

androgen receptor content and probably the actual expression of the AR. So when you actually have

an anabolic steroid or anandrogen like testosterone and it's circulating around, it binds to the

endergen receptor. Subsequent to that, you have androgen-induced RNA transcription at the

receptor site. So this is what ultimately causes the gene expression and causes the muscle

growth in the muscle protein synthesis, not the amount circulating in your blood. So if you have a

suboptimal amount of androgen receptors, or you have less myonuclei, or you have a suboptimal amount of androgen receptors or you have less myonuclei

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