meta_pixel
Tapesearch Logo
Freakonomics Radio

615. Is Ozempic as Magical as It Sounds?

Freakonomics Radio

Freakonomics Radio + Stitcher

Documentary, Society & Culture

4.632K Ratings

🗓️ 12 December 2024

⏱️ 57 minutes

🧾️ Download transcript

Summary

In a wide-ranging conversation with Ezekiel Emanuel, the policymaking physician and medical gadfly, we discuss the massive effects of GLP-1 drugs like Ozempic, Wegovy, and Mounjaro. We also talk about the state of cancer care, mysteries in the gut microbiome, flaws in the U.S. healthcare system — and what a second Trump term means for healthcare policy.

Transcript

Click on a timestamp to play from that location

0:00.0

The United States is one of just two countries that allow pharmaceutical firms to freely advertise their products directly to consumers.

0:10.7

The other is New Zealand. So if you ever watch TV in the U.S., you have likely seen many ads for prescription drugs.

0:19.3

But advertising doesn't guarantee success. The research and development

0:23.6

of these drugs is very expensive, and most of them never earn back their investment.

0:28.7

The pharmaceutical industry, therefore, relies on the occasional blockbuster drug. A blockbuster

0:34.9

defined is doing more than a billion dollars a year in sales.

0:38.4

If I asked you to name a blockbuster drug from the past, you might say Lipitor, a statin, originally from Park Davis, or Humera, an anti-inflammatory, now sold by Abbe.

0:50.6

And can you name a current blockbuster?

0:53.7

The first drug that comes to mind might be this one.

1:00.5

If you watch even a tiny bit of TV, you've probably seen an ad for Ozempic.

1:05.2

Their jingle is sung to the tune of the 1974 pop hit magic by a band called Pilot, which had exactly one U.S. hit.

1:16.4

Ozenpik, which is sold by the Danish multinational Novo Nordisk, is not a one-hit wonder.

1:22.9

It is one of a group of drugs known as GLP-1s, and many Americans would agree that they are magic.

1:32.2

GLP stands for glucagon-like peptide, which is a hormone produced in the human gut, and these

1:39.1

drugs mimic the activity of that hormone.

1:42.3

OZemPEC was developed to treat type 2 diabetes, which used to be called adult onset

1:47.3

diabetes to distinguish it from the more serious type 1 diabetes, which most often occurs

1:52.4

in young people.

1:53.5

But those lines have blurred, as many more people around the world, including a lot of

1:58.3

young people, are now getting type 2 diabetes.

2:01.8

Diabetes is a condition whereby the pancreas can't produce enough insulin to modulate your

2:07.1

level of glucose or blood sugar. Over the long term, high blood sugar can lead to all kinds of

...

Transcript will be available on the free plan in -110 days. Upgrade to see the full transcript now.

Disclaimer: The podcast and artwork embedded on this page are from Freakonomics Radio + Stitcher, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Freakonomics Radio + Stitcher and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2025.