#81 - Aging, Alzheimer’s, and Sleep with Dr. William Jagust

The Matt Walker Podcast

Dr. Matt Walker

Medicine, Science, Social Sciences, Health & Fitness

4.8 • 995 Ratings

🗓️ 9 September 2024

⏱️ 79 minutes

🔗️ Recording | iTunes | RSS

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Summary

Dr. William “Bill” Jagust, renowned expert in brain science and Alzheimer’s research - and one of the reasons Matt chose to move to UC Berkeley - joins our host today for an in-depth discussion on aging, cognitive decline, and the critical role of neuroimaging, with some sleep talk woven in as well. Dr. Jagust shares groundbreaking insights into how PET scans can detect amyloid and tau proteins in the brain—two key contributors to Alzheimer’s disease—years before symptoms emerge. Together wit...

Transcript

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0:00.0	Hi there. It's Matt Walker here and welcome back to the
0:06.4	podcast and welcome to a very special episode one that I've been desperate to
0:12.4	record for some time. This is about aging and
0:16.3	Alzheimer's disease and we will be weaving in commentary on sleep. I've already done a podcast previously on the interaction
0:25.2	between sleep and Alzheimer's disease and I'm sure we will come back to some of those
0:29.6	features but I have been working in the aging field since I was a much younger man when I was
0:37.8	starting my PhD and it's continued throughout my career but with a very strong sleep focus.
0:47.0	Nevertheless, when it comes to the field of aging and Alzheimer's disease, I'm not an expert.
0:54.3	And when you want to discuss this topic because of its seriousness,
0:59.1	you reach out to an expert.
1:02.1	One of the reasons that I ended up leaving Harvard Medical School and
1:06.4	joining UC Berkeley was because of the gentleman I'm about to speak with and that is
1:12.4	Dr. William Jagus or Bill Jagus and you will even call him
1:16.8	Bill because we're on good terms is that correct Bill?
1:20.8	Oh yes.
1:21.9	Well it's fine now. Thank you very much. Is that a little bit of correct, Bill? Yes.
1:23.0	Thank you very much.
1:24.0	Bill, when you hear people speak about
1:27.0	legends in their fields, you can think,
1:29.0	eh, is that a little bit of sycophancy?
1:31.0	But occasionally, there are true legends in their field.
1:35.8	Bill is that in the field of brain science he is a neurologist and he does gosh all sorts of work but one of his core research
	...

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