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🗓️ 1 July 2024
⏱️ 22 minutes
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Curcumin (Tumeric) is one of our favorite supplements! Not only does it benefit your gut and brain health, it’s also a powerful anti-inflammatory! Learn about the best dosage and usage of curcumin - watch now!
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And if you have any questions or topics you would like covered in the future, let me know in the comments!
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📉Effects of Turmeric and Curcumin Dietary Supplementation on Microbiota:
https://pubmed.ncbi.nlm.nih.gov/30088420/
📉Effect of polyphenol compounds on Helicobacter pylori eradication: https://pubmed.ncbi.nlm.nih.gov/36604137/
📉Turmeric extract may improve IBS symptomology:
https://pubmed.ncbi.nlm.nih.gov/15673996/
📉Efficacy of a curcumin extract (Curcugen™) on gastrointestinal symptoms and intestinal microbiotas: https://pubmed.ncbi.nlm.nih.gov/33478482/
📉Efficacy of Curcumin on Cognitive Function Scores in Women with Premenstrual Syndrome and Dysmenorrhea: https://pubmed.ncbi.nlm.nih.gov/37119345/
📉The Effect of Curcumin Differs on Individual Cognitive Domains across Different Patient Populations: https://pubmed.ncbi.nlm.nih.gov/34959636/
📉Curcumin intervention for cognitive function in different types of people: https://pubmed.ncbi.nlm.nih.gov/30575152/
📉Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice: https://pubmed.ncbi.nlm.nih.gov/24596618/
📉Curcumin Ingestion Inhibits Mastocytosis and Suppresses Intestinal Anaphylaxis in a Murine Model of Food Allergy: https://pubmed.ncbi.nlm.nih.gov/26147007/
📉Curcumin-mediated regulation of intestinal barrier function: https://pubmed.ncbi.nlm.nih.gov/29420166/
📉Curcumin and proton pump inhibitors for functional dyspepsia: https://pubmed.ncbi.nlm.nih.gov/37696679/
📉Curcumin use in ulcerative colitis: is it ready for prime time?: https://pubmed.ncbi.nlm.nih.gov/31892798/
📉Profiling Inflammatory Biomarkers following Curcumin Supplementation: https://pubmed.ncbi.nlm.nih.gov/36700039/
📉Effect of curcumin on proinflammatory cytokines: https://pubmed.ncbi.nlm.nih.gov/33934954/
📉Efficacy and safety of curcumin therapy for knee osteoarthritis: https://pubmed.ncbi.nlm.nih.gov/38036015/
📉Effect of curcumin on rheumatoid arthritis: https://pubmed.ncbi.nlm.nih.gov/37325651/
📉The Effects of Nano-Curcumin Supplementation on Cardiovascular Disease:
https://pubmed.ncbi.nlm.nih.gov/34202657/
📉The effects of curcumin on anthropometric and cardiometabolic parameters of patients with metabolic diseases: https://pubmed.ncbi.nlm.nih.gov/35475714/
📉Profiling Inflammatory Biomarkers following Curcumin Supplementation: https://pubmed.ncbi.nlm.nih.gov/36700039/
📉Curcumin use in ulcerative colitis: is it ready for prime time?: https://pubmed.ncbi.nlm.nih.gov/31892798/
📉Effects of curcumin on blood pressure: https://pubmed.ncbi.nlm.nih.gov/37567790/
📉Effects of curcumin/turmeric supplementation on liver function in adults: https://pubmed.ncbi.nlm.nih.gov/37178581/
📉Effects of curcumin/turmeric supplementation on lipid profile: https://pubmed.ncbi.nlm.nih.gov/37230418/
📉Curcumin Formulations for Better Bioavailability: https://pubmed.ncbi.nlm.nih.gov/37008131/
📉Methods Used for Enhancing the Bioavailability of Oral Curcumin:
https://pubmed.ncbi.nlm.nih.gov/36015087/
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*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
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0:00.0 | Welcome to Dr. Rucho Radio, providing practical and science-based solutions to feeling your best. |
0:14.8 | To stay up to date on the latest topics, as well as all of our prior episodes, make sure to subscribe in your podcast player. |
0:22.2 | For weekly updates, visit Dr.ruciot.com. |
0:25.6 | Hey, everyone, welcome back. Let's discuss curcumin. |
0:27.6 | This is a supplement that I think you should consider taking. |
0:30.5 | I take it daily have been doing so for a number of years. |
0:33.8 | There's ample research showing this is an impressive anti-inflammatory amongst other mechanisms. |
0:39.3 | So let's run through the dose, the form, and most importantly the benefits. |
0:44.1 | And starting off with where the benefits come from, where the gut, the brain, the joint, and the inflammatory benefits come from. |
0:53.7 | Likely the furthest upstream these benefits come |
0:57.2 | from is how curcumin can modulate the source of inflammation. So not even the inflammation |
1:03.8 | directly, but, and as you're seeing in this diagram, NF-capa- B is actually upstream to inflammation. |
1:15.2 | If we're calling cytokine, these inflammatory molecules, inflammation, then upstream to |
1:20.1 | inflammation, you have the NF Kappa B pathway, and this actually regulates genes, creation of inflammatory proteins, |
1:30.6 | and even what's known as the inflammasone, sort of this upstream network of gene regulation |
1:36.9 | and protein transcription that then leads to inflammation downstream. So this might be why |
1:42.8 | curcumin in particular is so powerful as an |
1:46.7 | anti-inflammatory. And again, that's what this diagram is helping to depict where curcumin |
1:51.0 | modulates the NF Kappa B pathway. And this leads to improvements in other cytokines that we've |
2:00.5 | discussed before, things like |
2:02.4 | interleukin beta, interleukin, 1 beta, interleukin 6, and tumor necrosis factor alpha or TNF |
2:09.7 | Alpha. So, this is what I find compelling and exciting about curcumin. Now, also, |
... |
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