Friends,

I recently sat down with Dr. Colleen Cutcliffe, CEO of Pendulum Therapeutics, for a discussion about probiotics, metabolism, and a potential natural alternative to GLP-1 drugs like Ozempic. Here's why I'm excited to share this with you...

The Backstory

A month ago, I ran into a friend who had slimmed down and was looking fit. These days, I’ve had a good dozen or so friends lose weight with GLP-1 drugs, so I was surprised when she told me it wasn’t Ozempic but Pendulum's new GLP-1 probiotic. Her chocolate cravings (her usual downfall) had changed entirely. Instead of demolishing a whole bar, she could have one bite and walk away satisfied.

I've known Pendulum for years (we invested at True), and I've personally used their glucose control product with great success. However, I had lost touch with Colleen and didn’t realize they had a new GLP-1 product — so I asked her to come on the podcast and discuss it.

Note: Peter Attia did a much longer and more thorough deep-dive with Colleen, found here

What Makes This Different?

In my interview with Colleen, she explained how their probiotic actually helps your body produce its own GLP-1 hormone naturally. The science is fascinating – they've identified specific strains of bacteria that, when delivered to your gut's distal colon, help stimulate natural GLP-1 production. No shots, no prescription.

The results are pretty impressive; 91% of users reported reduced food cravings after six weeks*, and the higher the initial cravings, the more significant the improvement.

Why This Matters

Over the last year+, I've watched friends scramble to find GLP-1 prescriptions, hitting up sketchy compounding pharmacies, or paying astronomical prices when their insurance won't cover them. It's wild out there.But obesity isn't just about weight – it's tied to heart disease, diabetes, cancer, and even cognitive decline (some scientists are calling Alzheimer's "Type 3 diabetes"). We need better solutions that are both accessible and backed by science.

Join Our Mini-Trial

Here's the exciting part: I’ve worked with Pendulum to create a special trial program exclusively for this newsletter community.

As always, full disclosure: True Ventures, where I work, is an investor in Pendulum. That said, I receive zero compensation for this trial; this is not a paid ad in any capacity. Here's why I'm excited to do this:

* I use their products myself (they’ve really helped my gut)

* Friends are now experiencing positive results

* I love the idea of an affordable natural solution

My most valuable asset is your trust. That's why I worked with Colleen to offer a 100-day money-back guarantee (they avoid this due to potential abuse/fraud). If you try it and come back saying, "Kevin, this did nothing for me," email Pendulum, and you'll get a refund. Simple as that.

Here's what you'll get in the trial

* Food Cravings Inventory diagnostic test at 0, 45, and 90 days to track your progress

* Direct access to microbiome specialists (bypassing regular customer service)

* 20% discount on your next order if you see positive results

* Contribute to real-world research data

* 100-day money-back guarantee

How to Join

Quick heads up on how this works: You'll need to purchase a 90-day supply upfront, but using my link unlocks the full money-back guarantee if it doesn't work for you – this is something not available anywhere else on their site. Click here to get started. (you must use this link)

What's Next?

We'll be collecting data throughout the trial and sharing the results with participants. Stay tuned for updates on how the community is progressing.

Exciting stuff ahead! As always, I'd love to hear your thoughts and experiences if you decide to participate.

Until next time, be well,

*based on a consumer survey of 274 people

This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.kevinrose.com/subscribe