Hey all, welcome back to the real-life pharmacology podcast. I'm host pharmacist Eric Christensen.

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All right, let's get into the drug of the day today, and it is dextraumphetamine and

amphetamine combination of amphetamine derivatives. Brand name is anterol, which it's probably more

commonly referred to as. This medication is

used primarily what I see in practice is for ADHD, tension deficit hyperactivity disorder,

as well as narcolepsy can be used for that as well. In my practice in geriatrics, rarely I have seen it used to basically

stimulate energy, combat fatigue. This is absolutely an off-label use in patients who are rehabbing and elderly patients, that type of thing.

I've seen it a few times.

Don't love seeing it because we've got plenty of potential adverse effects and risks associated with this class,

particularly in geriatric patients.

But I did want to mention that kind of additional use that I have seen off-label.

Mechanistically, how does this combination work, amphetamines and dextra-infetitone?

So essentially they are non-catecholamine-sympathometic amines that promote the release of catacolamines.

And, okay, what are catacolamines?

Well, think dopamine and think noropenephrine.

I mean, those are the two primary ones that this medication is essentially going to increase

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