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Diet vs. Lifestyle vs. Medication - Peter Attia's Approach To Determining The Best Strategy To Address Elevated apoB

More Plates More Dates

More Plates More Dates

Health & Fitness, Science, Education, Self-improvement

4.9 β€’ 806 Ratings

πŸ—“οΈ 29 November 2024

⏱️ 5 minutes

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Transcript

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0:00.0

Perhaps this is a too elaborate question to ask you to consolidate in like a summarized way,

0:05.7

but when it comes to evaluating lipid metabolism to actually determine which medication is the

0:11.8

viable therapy to consider, obviously not medical advice, how would you like I've seen some of the,

0:19.5

like you've described before some of the things you look at that

0:21.7

are not typical with, you know, elevations and sterols and whatnot. Yeah, yeah. Like, how would you go

0:27.0

about just at a, I don't know, even a recommendation of a certain panel that you like getting or

0:33.7

something that evaluates what you consider to be like a good foundation of this

0:38.5

is at least the biomarkers in question to evaluate the metabolism of your individual situation.

0:44.9

Yeah, if I see somebody's APOB and they're elevated, right?

0:47.7

So they have what's called hyper beta lipoproteenemia.

0:50.2

That's the technical word we're using to talk about this.

0:53.0

Elevated APOB.

0:56.5

I'd want to know the following.

0:59.1

How high are there triglycerides?

1:02.3

What are their markers of metabolic health?

1:05.2

What are there markers of cholesterol synthesis?

1:07.9

We typically measure desmosterol and lithosterol.

1:10.5

What are their markers of cholesterol absorption? We typically look at cytosterol and Lothosterol. What are their markers of cholesterol absorption?

1:16.2

We typically look at cytosterol and compestral.

1:27.3

If I know those things, then I have like a decent sense of how hard to pull on the diet lever. One other thing I want to know is what's

1:32.0

their saturated fat intake. So everything I just said, plus tell me what your saturated fat

1:36.8

intake is approximately in grams per day. And then if I know all of those things, then we

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