Welcome, my name is Devine. This is episode 474 of the Divine Intervention

Podcasts. And today's podcast we're going to be continuing the series on

the Aichronergic Receptors. Again, as we've mentioned, they're pretty high-yold things to understand.

So I've had a podcast already on the Alpha One receptor, a podcast on the Alpha 2 receptor, there's going to be a podcast on the

beta 2 receptor. And the beta, I mean the beta 1 receptor, sorry, and the beta 1 receptor

is a pretty straightforward receptor.

I'm just like again every eigenergic receptor it's a g-protein coupled receptor and it's a

stimulatory g-protein-cobole receptor. So what happens? Basically, if a ligand binds to it, so something like you're going to have an activation of a denylate cyclase and a

denylate cyclase as we know its job is to convert ATP to cyclic

imp and that cyclic imp is going to activate protein kinase A and that's going to cause a lot of different things.

And honestly, on the USMLEs, there are two high-yield places to know as to all, this is where the,

this is where Bidoone receptors are, because honestly there are many places you can find

this in the body. Well typically on the USMA exams there are kind of a few select

places they love to go after

And what are those two places? Well, the one big place is going to be in your kidneys

at your drugstore glomerular cells and then the second big place is going to be in your heart.

Your cardiac myocytes, your IV node, your S. A node, the beta one receptors in many places.

And basically what's the effect so So maybe let's look at each organ.

Again if you notice from the others what I've tried to do is to you know give a quick

introduction and then we'll start making some integrations here but basically in the heart these things

the middle one receptor's job is to raise your cardiac output

So I really begin to see that this may be helpful

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