4.9 β’ 806 Ratings
ποΈ 6 October 2024
β±οΈ 16 minutes
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0:00.0 | By the way, how important is D.H.T. Post-puberty? Seemingly, it depends because from a cognitive |
0:08.8 | health perspective, from a balance of estrogen standpoint, from a vasodilation in the penis standpoint, |
0:16.2 | like there are certain things where you could say it's pretty critical, but then there's |
0:19.7 | also, you could just as |
0:21.5 | easily say it's not necessary or mandatory. Like you will survive and likely thrive just the same |
0:28.0 | with a lack of DHD almost entirely. Even when you, a lot of people will demonize five alpha |
0:35.2 | reductase inhibitors and justifiably so in some cases. But even when you look |
0:40.5 | to literature that compares placebo versus finasteride versus deutasteride, side effect profiles are |
0:46.2 | pretty similar even. Yeah, due tasteride and fanasteride being two drugs that block 5 alpha |
0:51.9 | reductase used initially for reducing prostate size because DHT disproportionately drives prostate growth, |
1:00.2 | but also used for hair, I think, I would say use more for hair loss now. |
1:04.3 | Yeah. |
1:06.6 | But yes, and we have talked about this on two podcasts previously about post-finasteride |
1:11.0 | syndrome, um, which is a debatable idea. |
1:15.2 | In other words, there is not a clear consensus in the urologic literature about even the |
1:20.2 | existence of this, let alone the prevalence, let alone the reversibility of it. |
1:27.0 | All of these things are really unknowns. And actually, |
1:32.2 | it's created quite, quite a bit of a conundrum for us because we have a number of patients who take |
1:37.1 | fanasteride or dexteride for hair loss. And what's your stance on five alpha reductase inhibitors just at a? Yeah, I mean, |
1:47.9 | look, I think, I'll be honest with you. I never really paid enormous attention to it until about a |
1:53.3 | year ago. And I think right now our stance is I probably wouldn't start somebody on it. |
2:02.6 | And if a person, so in other words, if a person has BPH, we're not going to manage that anyway. |
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