meta_pixel
Tapesearch Logo
Science Quickly

How Are Prenatal Blood Tests Detecting Cancer?

Science Quickly

Scientific American

Science

4.31.4K Ratings

🗓️ 11 April 2025

⏱️ 21 minutes

🧾️ Download transcript

Summary

Noninvasive prenatal blood testing, or NIPT, is a routine screening that is offered during pregnancy and looks for placental DNA to diagnose chromosomal disorders in a fetus. But in some cases, these tests can also find cancer in the pregnant person. How do the tests work, and why are they uncovering cancer? Genetic counselor and writer Laura Herscher speaks with host Rachel Feltman about IDENTIFY (Incidental Detection of Maternal Neoplasia through Non-invasive Cell-Free DNA Analysis), a broader study that seeks to understand why usual results from NIPT can correlate with a cancer diagnosis in a pregnant patient. Plus, we discuss why treating pregnant patients for cancer can be complicated for obstetricians and oncologists. Recommended reading: A Prenatal Test of the Fetus Turns Up Cancers in Pregnant Mothers https://www.scientificamerican.com/article/a-prenatal-test-of-the-fetus-turns-up-cancers-in-pregnant-mothers/  E-mail us at [email protected] if you have any questions, comments or ideas for stories we should cover! Discover something new every day: subscribe to Scientific American and sign up for Today in Science, our daily newsletter.  Science Quickly is produced by Rachel Feltman, Fonda Mwangi, Kelso Harper, Naeem Amarsy and Jeff DelViscio. This episode was hosted by Rachel Feltman. Our show is edited by Alex Sugiura with fact-checking by Shayna Posses and Aaron Shattuck. The theme music was composed by Dominic Smith. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

Click on a timestamp to play from that location

0:00.0

Hi, I'm Clara Moskowitz, senior editor for space and physics at Scientific American.

0:05.0

Like many kids, I once dreamed of becoming an astronaut.

0:08.0

While I never made it to space, my work at Scientific American has given me the next best thing,

0:13.0

exploring the cosmos through stories and sharing its wonders with science lovers like you.

0:19.0

When I research a story, I immerse myself in the reporting

0:21.9

to bring you an exciting and accurate account. Over the years, I've covered breathtaking rocket

0:26.9

launches, visited one of the world's highest altitude telescopes in Chile, and even trained for

0:32.2

suborbital spaceflight. Space is vast, beautiful, and full of the unexpected. Taking a moment to look beyond our daily routines and reflect on its mysteries can be a powerful escape.

0:44.1

Join me on this journey of discovery.

0:46.4

Subscribe to Scientific American today at siam.com slash getsyam.

0:51.4

Music slash get siam.

1:25.6

For Scientific American Science Quickly, non-invasive prenatal blood testing, or NIPT, has been a fairly routine aspect of pregnancy care. This testing searches a pregnant person's blood for fragments of DNA that have been shed by the placenta.

1:31.3

NIPT is designed to spot chromosomal disorders in the fetus, but in rare cases the blood test can detect something else.

1:39.3

Cancer in the parent.

1:41.3

My guest today is Laura Herscher, a genetic counselor and director of student research at the

1:46.4

Sarah Lawrence College Joan H. Mark's graduate program in human genetics.

1:51.2

She recently wrote a piece for Scientific American about the researchers working to understand

1:55.5

how NIPT finds cancer in some pregnant people.

1:59.3

She's here to tell us more about the incidental detection of

2:02.1

maternal neoplasia through non-invasive cell-free DNA analysis study, or Identify for short.

2:07.8

Laura, thank you so much for coming on to chat today. So you recently wrote about something

2:11.8

called the Identify study. How did you get interested in the story? Well, the first time I heard about

...

Transcript will be available on the free plan in 14 days. Upgrade to see the full transcript now.

Disclaimer: The podcast and artwork embedded on this page are from Scientific American, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Scientific American and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2025.