Is your liver full of fat? | Christos Mantzoros MD, DSc, PhD

The Proof with Simon Hill

Simon Hill

Nutrition, Health & Fitness, Self-improvement, Education

4.9 • 2.9K Ratings

🗓️ 15 July 2024

⏱️ 91 minutes

🔗️ Recording | iTunes | RSS

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Summary

Episode #322. Did you know that 30% of cancers are related to obesity? Join me as I sit down with Harvard Professor and endocrinologist Dr Christos Mantzoroz to discuss fatty liver disease, metabolic health, and hormones. You’ll learn about why so many people are obese and whether you can be overweight and healthy. Dr Mantzoroz breaks down budget-friendly ways to evaluate your metabolic health, explains how hormones affect your weight, and offers his insight on how to treat obesity. Overall, this episode is a masterclass in metabolic health and fatty liver disease. Specifically, we discuss: Introduction to The Latest Obesity Research Findings (00:00) The Evolving Understanding of Obesity Science (03:49) Uncovering New Fat Storage Mechanisms (10:57) Modern Techniques for Accurate Body Fat Measurement (15:02) Why Maintaining Weight Loss Is So Challenging (20:01) Evolutionary Insights into Human Fat Storage (25:12) How Leptin Regulates Energy Balance and Health (29:17) New Approaches to Break Through Weight Set Points (39:27) Environment's Role in Weight Gain Beyond Diet (45:49) Decoding the Genetics of Fat Storage and Metabolism (52:59) Non-Alcoholic Fatty Liver Disease Explained (55:40) Evidence-Based Nutrition for Optimal Liver Health (01:05:25) Promising Advances in Non-Invasive Liver Tests (01:10:49) Oestrogen's Impact on Metabolism (01:20:14) The Link Between Liver Fat and Insulin Resistance (01:22:04) Addressing America's Growing Metabolic Health Crisis (01:26:11) Outro (01:27:11) Connect with Christos Mantzoros, MD DSc PhD h.c. mult. on LinkedIn, and discover his work here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcript

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0:00.0	In today's episode, I sit down with Professor Christos Mansoros.
0:05.0	Dr Mansoros is a professor of medicine at Harvard University and a clinical endocrinologist.
0:12.0	He's one of the most published scientists and a clinical endocrinologist.
0:12.6	He's one of the most published scientists in the world
0:15.8	interested in nutrition and metabolism,
0:18.4	with a specific interest in metabolic syndrome,
0:20.9	type 2 diabetes, and fattyty Liver Disease. Today's focus being on the latter, Fatty Liver Disease.
0:27.0	Please enjoy. My favorite multivitamin by a long stretch is a meal's essential 8, the right nutrients
0:38.8	and the right doses to support a healthy plant-rich diet, optimize nutrient status, and leave you feeling at your best.
0:46.1	Take your health to another level with a meal's evidence-based essential-eight multivitamin
0:51.4	by going to a meal.com forward slash Simon for 20% off your first purchase and 10% off repeat purchases.
0:59.0	That's EIME, E, E, E, E, E, E, E, E,S-E-S-S-E-S-S-T for 20-E-E-T-S-T-E-S-S-S-O-S-E-S-S-S-S-E-S-S-S-S-S-E-S-E-E for 20 Hey friends the scientific evidence on lifestyle habits that lead to
1:18.3	longevity is clear now it's time to put this knowledge into action.
1:23.0	I'm excited to announce the Living Proof longevity Challenge,
1:26.0	a 12-week program to build evidence-based lifestyle habits
1:30.0	to optimize longevity.
1:32.0	My team and I have transformed over hundreds of hours of conversations
1:35.6	with experts on aging, nutrition and exercise into a life-changing 12-week program
1:41.6	that will challenge you to develop habits that lead to a longer better life.
1:46.5	This is a unique opportunity to gather health data about yourself that has the potential to change your life for the better.
1:54.0	You'll start by testing 10 longevity biomarkers that tell the truth about where your longevity stands right now, today.
2:02.0	Following that, you'll get a personalized longevity score
	...

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