The Proof with Simon Hill

How can we protect our brain as we age and what can we do today to boost memory, focus, and resilience? In this episode of The Proof, I’ve compiled some of the most impactful conversations I’ve had with leading neuroscientists, neurologists, and brain health researchers to explore exactly that. From building better habits to slowing age-related decline, this masterclass brings you practical, science-backed strategies for optimising brain function, now and in the future. Whether your goal is sharper mental clarity, prevention of neurodegenerative disease, or simply staying sharp for the long haul, this episode is packed with insights you can use right away. You’ll learn: • How neuroplasticity allows your brain to adapt and change at any age • The role of movement and VO₂ max in protecting cognitive performance • How omega-3s and dietary fats impact brain structure and function • What APOE4 means for your risk of Alzheimer’s and why genetics aren’t destiny • The link between cardiovascular health, lipoproteins, and dementia • How the microbiome and inflammation influence brain aging • The surprising ways exercise improves brain volume and connectivity • Why creatine isn’t just for muscles and how it may enhance mental energy and mood • Actionable daily habits to reduce your risk of cognitive decline • The truth about lifestyle vs genetics when it comes to Alzheimer’s disease Featuring insights from Dr Andrew Huberman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Thomas Dayspring, and Dr Kellyann Niotis, this episode distills cutting-edge neuroscience into clear, practical guidance for long-term cognitive health. Thank you for tuning in to today’s episode, and special thanks to the experts featured for their invaluable insights. If you found this episode helpful, please share it with someone who you think might benefit from it. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 21 April 2025

In today’s episode Dr Matthew Nagra returns to The Proof to break down a new JAMA Internal Medicine study on butter, plant-based oils, and mortality. Over 200,000 Americans were followed for 33 years — so what did the research really find? We unpack the study’s most talked-about claims, including whether swapping just 10g of butter for plant-based oil could lower your risk of early death. Plus, we dive into the bigger picture: Why fats are so polarising, the debate around seed oils, and how to navigate nutrition science in an era of misinformation. Specifically, we cover: Inside a Controversial New Study on Butter and Plant Oils (00:00) How the 33-Year Nutrition Study Was Conducted (00:47) What Observational Studies Can (and Can’t) Tell Us (03:01) The Truth About Food Frequency Questionnaires (08:03) Surprising Patterns in Butter and Oil Consumption (17:52) Why One Common Oil Performed Better Than Expected (22:50) Are We Misunderstanding Nutrition Guidelines? (26:13) What Happens When Oils Are Heated Over and Over (28:28) Do Oils Measure Up to Whole Food Fat Sources? (31:04) The Great Oil Debate: A Preview and Reflection (34:07) A Smarter Way to Navigate Conflicting Health Advice (43:40) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 14 April 2025

What if losing body fat didn’t have to be so difficult? In this episode, I share five practical, science-backed strategies to support fat loss in a sustainable way. No gimmicks. No pseudo-science. Just real tools to help you feel fuller, fuel your body better, and improve metabolic health. Whether your goal is to reduce visceral fat or feel more confident in your body, these strategies can help — and you don’t need to do them all at once to see results. In this episode, I cover: Why energy density matters The “preload” trick that helps regulate intake How eating slower naturally reduces appetite The surprising role of gut microbes in hunger Why protein + fibre is the ultimate combo A flexible approach to time-restricted eating Plus, I bust common weight loss myths and share why improving body composition is about more than aesthetics. If you’re ready for a science-based, sustainable approach to fat loss — without restriction — this episode is for you. Introduction (00:00) Should You Choose Low Energy Dense Foods? (01:39) Could Slowing Down Your Eating Help? (07:51) How Can You Feed Your Gut Microbes? (12:29) Why Increase Your Protein Intake? (15:41) Does Reducing Your Eating Window Work? (19:27) Recap and Final Thoughts (21:03) Conclusions (22:16) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for 25% at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 8 April 2025

Welcome to the very first episode of a brand new format - something a little more relaxed, more personal, and more conversational. Think of this as us sitting on the couch or going for a long walk together. No script. No structure. Just your questions, and my honest thoughts. In this episode, I answer your voice notes and DMs - covering: Intro (00:00) How Can New Fathers Balance Fitness and Diet with a Busy Life? (02:20) What Are the Risks and Benefits of Methylene Blue? (12:20) What Are the Biggest Nutrition Myths Still Believed in 2025? (16:59) Why Do Some Plant-Based Eaters Still Have High Cholesterol? (19:52) What Are the Best Alternatives to Statins for Lowering APOB? (23:32) What Health Habits Does Simon Hill Personally Struggle With? (32:41) Are Refined Carbohydrates Like Pasta and White Rice Actually Bad for You? (34:09) What’s the Future of Personalised Nutrition? (40:16) What’s the Most Embarrassing Travel Story Simon Has Shared? (44:33) What Does “Bogan” Mean in Australian Slang? (47:49) How Much Omega-3 Do You Really Need Daily? (50:06) Does Creatine Supplementation Harm Your Kidneys? (56:10) What’s the Perfect Meal for Human and Planetary Health? (01:00:31) Can the Power of Belief Affect Your Health Outcomes? (01:03:05) What’s the Funniest Listener Question and Final Thoughts? (01:04:11) Some serious, some silly - but all of it real. I hope you enjoy this new format, and as always, I’d love your feedback. Let me know what you liked, didn’t like, and what you’d love to see more of in future episodes. If you’d like to leave a question for a future Q&A episode, you can do that in the YT comments or send a message on IG instagram.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 31 March 2025

Are seed oils actually harmful? Or is this just another wellness myth gone viral? In this episode, I sit down with Dr. Bill Harris - leading expert on dietary fats - to unpack the science on linoleic acid, an omega-6 fat found in nuts, seeds, and vegetable oils. We explore the rise of seed oil fear-mongering, the truth about inflammation, cholesterol, oxidation, and why outcome data—not mechanisms—should guide our thinking. Omega-6 Fats and Health Overview (00:00) Why the Review Was Updated (01:22) What Is Linoleic Acid? (06:47) Linoleic Intake Over Time & Health Links (12:45) Research Methods and Key Evidence (16:25) Omega-6 and Inflammation Explained (41:00) Common Myths About Seed Oils (44:37) The Oxidation Concern with Seed Oils (49:20) Omega-6 vs Omega-3: The Real Story (53:39) Blood Sugar, Insulin & Linoleic Acid (01:03:48) Heart Health and Linoleic Benefits (01:05:44) Cancer Risk and Seed Oils (01:13:49) Public Health and Future Research (01:16:55) How to Use Vegetable Oils Wisely (01:25:17) Wrap-Up and Takeaway Advice (01:32:22) If you’ve been confused by the seed oil debate, this one’s for you. Visit The Proof website for the full show notes and supporting studies. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 25 March 2025

In today’s episode, I’m joined by Drew Harrisberg, an exercise physiologist, diabetes educator, and founder of Drew’s Daily Dose. We dive into the science behind Apple Cider Vinegar (ACV)—does it actually help with blood sugar, weight loss, digestion, and overall health, or is it just another overhyped wellness trend? We also explore the power of anecdotes in the wellness industry, starting with Belle Gibson’s story and the new Netflix series on ACV. How can we separate fact from fiction when faced with bold health claims on social media? What we cover: • ACV and blood sugar – does it really help? • ACV and weight loss – what does the science say? • ACV vs. other blood sugar strategies (walking, fiber, etc.) • Potential downsides – acid, teeth damage, capsules, and more • How to take ACV without ruining your teeth • Should Simon take Bragg’s ACV as a sponsor? Ethics of podcast ads Later, Drew shares a moving tribute to his dog, Dennis, reflecting on grief, love, and celebrating life. We also talk about memory dividends and why showing up for the people (and pets) we love matters. We wrap up with a shocking magic trick, plenty of laughs, and a classic dad joke. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 17 March 2025

This episode originally aired on The Adversity Advantage, hosted by Doug Bopst—a personal trainer, author, and former addict who transformed his life through fitness. His podcast dives deep into health, mindset, and resilience to help people unlock their full potential. In our conversation, we break down the science of longevity, nutrition, and optimal health. We discuss the best dietary patterns for longevity, the debate around red meat and seed oils, and why exercise is essential for long-term health. Topics Covered: What does the science say about longevity and diet? Are seed oils really harmful, or is the science misunderstood? The real risks of red meat and saturated fats for long-term health How ultra-processed foods impact metabolic health The importance of protein intake for longevity and muscle preservation Why exercise is just as crucial as diet for healthspan The Living Proof Challenge – a zero-cost 12-week longevity program Join the Living Proof Challenge: theproof.com/livingproof You can connect with Doug through his Podcast Website, where he shares insightful conversations on health, fitness, and personal transformation. Follow him on Instagram for daily inspiration and expert advice, subscribe to his YouTube channel for in-depth discussions and interviews, and stay updated with his latest thoughts on X. Introduction (00:00) Discussing the Best Dietary Patterns for Longevity (00:53) Debating Meat-Based Diets and Long-Term Health (04:33) Health Implications of Red Meat Consumption (09:54) Practical Steps for Improved Health & Longevity (22:50) Understanding Amino Acids and Protein Sources (34:01) The Importance of Exercise for Longevity (34:50) Exercise Protocols for Optimal Health (35:47) Resistance Training and Its Benefits (37:43) Cardio and Resistance Training Balance (41:30) Intermittent Fasting and Meal Timing (52:40) The Role of Light and Circadian Rhythms (56:20) Insights on Longevity and Nutrition (59:47) The Importance of Relationships for Happiness (01:04:01) Conclusion (01:09:17) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 11 March 2025

You may have heard claims that C:15 (pentadecanoic acid) is the first essential fat discovered in 90 years, a powerful longevity booster, and a game-changer for metabolic health. But how much of this is backed by solid science? In this episode, I sit down with Dr. Bill Harris, a leading expert in fatty acid research, to critically evaluate the evidence behind C:15. We break down the population studies linking it to health benefits, the key clinical trials testing its effects, and whether the marketing around Fatty15 is ahead of the actual data. In this episode, we cover: What exactly is C:15, and how does it compare to other fats? The claim that C:15 is an essential nutrient—does it meet the criteria? The current evidence on C:15 and its impact on cholesterol, glucose, and inflammation Does C:15 supplementation mimic omega-3s, metformin, or rapamycin? The broader issue of patenting a naturally occurring compound For more details and supporting studies, visit the full show notes. Introduction to Pentadecanoic Acid (C15) (00:00) Evaluating the Claims of C15 (02:05 Comparing C15 with Other Fatty Acids (03:12) Health Implications of Dairy Fats and the Essentiality of C15 (05:02) Scientific Evidence and Studies on C15 (13:12) Interpreting Clinical Trial Results, Cholesterol, and the Tango Trial (27:59) Cholesterol and the Tango Trial (28:28) Comparing C15 to Omega 3s (32:02) Future Research Directions for C15 (37:46) Longevity Claims and Patents (42:30) Final Thoughts and Conclusion (49:44) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 March 2025

You may have heard claims that C15:0 (pentadecanoic acid) is the first essential fat discovered in 90 years, a powerful longevity booster, and a game-changer for metabolic health. But how much of this is backed by solid science? In this episode, I sit down with Dr. Bill Harris, a leading expert in fatty acid research, to critically evaluate the evidence behind C15:0. We break down the population studies linking it to health benefits, the key clinical trials testing its effects, and whether the marketing around Fatty15 is ahead of the actual data. In this episode, we cover: What exactly is C15:0, and how does it compare to other fats? The claim that C15:0 is an essential nutrient—does it meet the criteria? The current evidence on C15:0 and its impact on cholesterol, glucose, and inflammation Does C15:0 supplementation mimic omega-3s, metformin, or rapamycin? The broader issue of patenting a naturally occurring compound For more details and supporting studies, visit the full show notes. Introduction to Pentadecanoic Acid (C15:0) (00:00) Evaluating the Claims of C15:0 (02:05 Comparing C15:0 with Other Fatty Acids (03:12) Health Implications of Dairy Fats and the Essentiality of C15:0 (05:02) Scientific Evidence and Studies on C15:0 (13:12) Interpreting Clinical Trial Results, Cholesterol, and the Tango Trial (27:59) Cholesterol and the Tango Trial (28:28) Comparing C15:0 to Omega 3s (32:02) Future Research Directions for C15:0 (37:46) Longevity Claims and Patents (42:30) Final Thoughts and Conclusion (49:44) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.  Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 March 2025

Is olive oil really as healthy as people claim? How does it compare to other fats? And how do you choose the best product for cooking and everyday use? In this episode, I take a deep dive into the science behind olive oil—its potential role in longevity, its impact on chronic diseases like cardiovascular disease and diabetes, and the key factors that determine quality. In this episode, we cover: Olive oil’s role in longevity and overall health The difference between refined and extra virgin olive oil How olive oil may influence cardiovascular, cognitive, and metabolic health What to look for when buying olive oil and how to store it properly Whether it’s safe to cook with olive oil and how to preserve its benefits For more details and supporting studies, visit the full show notes. Introduction (00:00) Olive Oil for Longevity and Lifespan (00:52) Olive Oil for Heart Health and Chronic Disease (06:28) Olive Oil’s Role in Cancer Prevention (07:58) Olive Oil for Brain Health and Cognitive Function (12:38) Olive Oil for Metabolic Health and Blood Sugar Control (16:08) How Olive Oil Supports Overall Health (21:12) How to Choose High-Quality Olive Oil (25:27) Best Practices for Cooking and Storing Olive Oil (35:12) Key Takeaways on Olive Oil’s Health Benefits (41:32) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Applied Nutrition Literacy Looking to sharpen your nutrition literacy and make smarter, science-based decisions? Enrol in the Applied Nutrition Literacy Course to gain the tools you need to evaluate research confidently. Perfect for nutrition professionals and keen enthusiasts. Join by March 8 here. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 25 February 2025

In this episode, I sit down with Drew Harrisberg to break down four new studies covering selenium intake, plant vs. animal monounsaturated fats, workout recovery strategies, and resistance training techniques. But beyond the science, we also discuss a critical issue in health communication—the responsibility of podcast hosts when platforming health claims. Using recent episodes of Diary of a CEO featuring Dr. Mindy Pelz and Dr. Sarah Berry, we examine how misinformation spreads, why extreme views persist, and how listeners can differentiate science from pseudoscience. Introduction (00:00) Ross Walker: The Comedian Cardiologist (03:23)\ The Importance of CGM and Misleading Health Advice (12:29) Scientific Method and Logical Consistency (24:29) Debunking Myths: Seed Oils and Health (32:59) The Power of Anecdotes vs. Scientific Evidence (42:54) Jordan Peterson and Elon Musk's Viral Clip (50:13) Personal Humility and Dietary Failures (53:07) Study on Recovery Modalities: Hot vs. Cold Baths (01:00:56) Minimum Effective Dose for Resistance Training (01:19:34) Selenium Intake and Brazil Nuts (01:31:14) Monounsaturated Fats and Type 2 Diabetes Risk (01:48:32) Concluding Thoughts (02:21:01) Key Discussion Points: Dr. Sarah Berry’s Diary of a CEO appearance and the backlash The seed oil controversy—do they really cause inflammation? How to spot red and green flags in health claims Four new studies on nutrition and exercise, including whether training to failure is necessary for muscle growth For more details and supporting studies, visit the full show notes: https://theproof.com/podcast/ The best way to support the show is to use the products and services offered by our sponsors. Visit http://theproof.com/friends for exclusive discounts. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 18 February 2025

In today’s episode of The Proof, we dissect a video featuring Dr. Gabrielle Lyon discussing protein sources and the importance of leucine for muscle building. I break down her claims, compare animal and plant protein sources, and explore the latest research on muscle protein synthesis and long-term health outcomes. Introduction (00:00) Dr. Lyon's Argument: Animal vs. Plant Protein (00:17) Critiquing Dr. Lyon's Protein Source Comparisons (01:14) Evaluating the Leucine Threshold Hypothesis (03:13) Plant-Based Protein Sources: A Deeper Look (06:30) Scientific Studies on Protein and Muscle Growth (15:40) Conclusion (25:17) Key Discussion Points: Dr. Lyon’s Claims Comparing Protein Sources The Leucine Threshold Debate Beyond Muscle Protein Synthesis Plus, if you watch/listen all the way to the end I share a fun personal story about my 90-year-old grandma who took up walking 10km a day! Enjoy, Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 11 February 2025

Think creatine supplementation is all about timing and loading? You might be surprised. In episode #350, I dive into six frequently asked questions about creatine, inspired by a follow-up review by Dr. Jose Antonio and colleagues. Whether you’re just starting with creatine or already supplementing, this episode will provide clarity and practical insights. Learn why timing matters less than consistency, whether co-supplements like carbs enhance effectiveness, and if creatine affects blood pressure, fertility, or urine production. This is your ultimate guide to making informed decisions about creatine supplementation. Key highlights include: Does the timing of creatine intake matter? Do other compounds enhance creatine’s effectiveness? Does creatine affect blood pressure or increase urine production? Is creatine safe to use during pregnancy? Can creatine supplementation impact male fertility? Discover insights and supporting studies in the full show notes. Introduction (00:00) Timing of Creatine Supplementation (02:50) Enhancing Creatine Effectiveness with Other Compounds (05:06) Creatine and Blood Pressure (06:31) Creatine and Urine Production (08:35) Creatine Safety During Pregnancy (10:56) Creatine and Male Fertility (12:49) Recap and Final Thoughts (14:37) Outro (17:12) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Notion Notion is the all-in-one workspace that helps you organise your work and life seamlessly. It’s been the backbone of The Proof since 2018, streamlining everything from guest bios and show notes to managing episodes. With Notion AI, you can take your productivity to the next level—generate ideas, summarise content, and organise tasks effortlessly. Try Notion for free at notion.com/theproof and experience the difference for yourself! Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 February 2025

In this episode of The Proof, I explore male fertility with Dr. Ramy Abou Ghayda, a leading urologist specialising in reproductive health. Together, we unpack the science behind sperm health, bust common myths, and provide evidence-based strategies for optimising male fertility. You'll discover: The truth about declining male fertility rates and what current research tells us How lifestyle factors like diet, exercise, and environmental toxins affect sperm health Evidence-based nutrition strategies and supplements for improving fertility Whether you should abstain from ejaculation in the days before intercourse when trying to conceive The impact of modern technology and daily habits on reproductive health Practical tips for protecting and enhancing male fertility at any age And much more Whether you're planning a family or simply interested in optimising your reproductive health, this conversation offers valuable insights and actionable advice from one of the field's leading experts. Introduction (00:00) Is Declining Male Fertility a Real Concern? (00:08) Understanding Semen Health and Fertility Basics (01:37) Breaking the Taboo: Male Infertility in Society (04:37) What Affects Male Fertility? Lifestyle, Environment, and More (09:14) Semen Analysis and Testing: Lab vs. Home Kits (18:18) Environmental Toxins, Lifestyle, and Fertility (23:31) Sperm Testing Options (30:50) Testosterone Therapy and Sperm Freezing (40:30) Lifestyle Changes to Boost Fertility (57:46) How Medications Affect Sperm and Erectile Function (01:12:34) Viagra, Cialis, and Psychological Aspects of Fertility (01:19:52) Timing Conception and the Fertile Window (01:24:24) Sleep’s Role in Male Fertility (01:36:31) Medical Interventions and Future Research (01:38:04) Future of Male Fertility Research and Innovations (01:45:27) Final Takeaways and Myths in Male Fertility (01:59:00) This episode is brought to you by: Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 20 January 2025

In this episode of The Proof, I explore male fertility with Dr. Ramy Abou Ghayda, a leading urologist specialising in reproductive health. Together, we unpack the science behind sperm health, bust common myths, and provide evidence-based strategies for optimising male fertility. You'll discover: The truth about declining male fertility rates and what current research tells us How lifestyle factors like diet, exercise, and environmental toxins affect sperm health Evidence-based nutrition strategies and supplements for improving fertility Whether you should abstain from ejaculation in the days before intercourse when trying to conceive The impact of modern technology and daily habits on reproductive health Practical tips for protecting and enhancing male fertility at any age And much more Whether you're planning a family or simply interested in optimising your reproductive health, this conversation offers valuable insights and actionable advice from one of the field's leading experts. Introduction (00:00) Is Declining Male Fertility a Real Concern? (00:08) Understanding Semen Health and Fertility Basics (01:37) Breaking the Taboo: Male Infertility in Society (04:37) What Affects Male Fertility? Lifestyle, Environment, and More (09:14) Semen Analysis and Testing: Lab vs. Home Kits (18:18) Environmental Toxins, Lifestyle, and Fertility (23:31) Sperm Testing Options (30:50) Testosterone Therapy and Sperm Freezing (40:30) Lifestyle Changes to Boost Fertility (57:46) How Medications Affect Sperm and Erectile Function (01:12:34) Viagra, Cialis, and Psychological Aspects of Fertility (01:19:52) Timing Conception and the Fertile Window (01:24:24) Sleep’s Role in Male Fertility (01:36:31) Medical Interventions and Future Research (01:38:04) Future of Male Fertility Research and Innovations (01:45:27) Final Takeaways and Myths in Male Fertility (01:59:00) This episode is brought to you by: Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 20 January 2025

Episode #348. Love isn’t just a feeling – it’s a skill. Relationship coach Jillian Turecki joins me to explore the habits, mindsets, and tools you need to build and sustain meaningful love. We explore the role of self-esteem, how to navigate conflict, and what makes a relationship worth fighting for. Packed with insights on compatibility, healthy communication, and cultivating love, this episode offers practical advice for every stage of your relationship journey. Specifically, we discuss: Love is a daily practice: How can we build it? (0:00) Understanding relationship breakdowns (8:18) How self-love shapes relationships (11:06) Challenges of loving ourselves (16:18) How to navigate conflict effectively (34:51) Addressing commitment and anxiety in love (40:00) When should you discuss your needs in a relationship? (43:44) The difference between connection and relationship (46:54) How to master conflict repair (49:48) Giving effective feedback in relationships (52:52) How to know when it’s time to leave (1:03:25) The rewards of a healthy relationship (1:09:45) Outro (1:14:50) Jillian Turecki’s book, It Begins With You, is available here. Connect with her on Instagram, Twitter/X, and TikTok. Learn more about Jillian and discover her courses at https://www.jillianturecki.com/. Listen to Episode #273 with Jillian here. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Notion Notion is the all-in-one workspace that helps you organise your work and life seamlessly. It’s been the backbone of The Proof since 2018, streamlining everything from guest bios and show notes to managing episodes. With Notion AI, you can take your productivity to the next level—generate ideas, summarise content, and organise tasks effortlessly. Try Notion for free at notion.com/theproof and experience the difference for yourself! Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 13 January 2025

Episode #347. Two friends, four studies, endless insights. Join me as I sit down with Drew Harrisberg to break down the latest in nutrition, fitness, and longevity, sharing surprising truths you won’t want to miss. Along the way, we reflect on my recent debate with Dr Robert Kiltz, exploring key takeaways and how they fit into the broader conversation about diet and health. Learn about the impact of smartphone use on workout performance, how many calories you really burn during exercise, and whether a large dose of creatine can conquer a poor night’s sleep. This episode is packed with groundbreaking research and practical tips to help you make more informed choices for your health. Specifically, we cover: Introduction (00:00) Catching Up with Drew Harrisberg (01:05) Upcoming Studies and Research (27:04) Meat vs Plants Debate Frustrations (39:58) Keto Diet and Metabolic Health (57:54) New Study: Smartphone Use and Workout Performance (01:04:47)\ New Study: High-Dose Creatine and Cognitive Performance (01:15:42) New Study: Energy Expenditure in Resistance Training (01:32:03) New Study: Plant vs Animal Protein and Cardiovascular Health (01:44:30) Living Proof Challenge Overview (02:02:45) Outro (02:12:23) To connect with Drew, you can reach him via his Instagram or website, Drew’s Daily Dose, where you can also find his training program. To hear more from Drew, check out his previous episodes on The Proof. Head to the full show notes for additional insights, resources, and supporting studies. Join the Living Proof Challenge at https://theproof.com/livingproof/. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 6 January 2025

Episode #346. Keen to commit to your health in 2025? Tune in for the ultimate cheat sheet, packed with the best insights from 2024 on nutrition, fitness, and longevity. This is your chance to reflect, reset, and step into the new year with actionable tips from the brightest minds in health and wellness. This special episode features wisdom from world-class experts, including Alan Aragon, Dr Kevin Maki, Dr Carol Kirkpatrick, Dr Nicholas Burd, Dr Venki Ramakrishnan, Dr Thomas Dayspring, Dr Kellyann Niotis, Dr Christos S. Mantzoros, Dr Karl Nadolsky, Dr Daniel Soffer, Dr Michael Hill, Dr Alyssa Olenick, Dr Jen Gunter, Robin Sharma, and Dr Christopher Gardner. Specifically, we cover: Introduction (00:00) Effective, evidence-based weight loss strategies (01:35) The importance of protein for health and metabolism (10:07) Unpacking the 30-30-30 framework for sustainable health (14:27) Optimal vs. Maximal Protein Intake for Muscle Growth (28:11) How lifestyle choices influence the science of ageing (32:03) The role of cholesterol in dementia risk (41:08) Diet Choices That May Help Prevent Dementia (48:41) Understanding the personal fat threshold in obesity (54:11) Strategies to reverse metabolic health challenges (58:10) Identifying High-Risk Indicators for Lipoprotein(a) (01:04:41) Debunking the Triglycerides-to-HDL Ratio Debate (01:17:30) Comparing ApoB and LDL Cholesterol in Cardiovascular Risk (01:25:48) Insights into microvascular dysfunction and cardiovascular health (01:34:19) Protein requirements for women and dietary guidance (01:45:12) Science-backed tips for muscle growth (01:51:06) Dispelling myths about menstrual health (01:55:00) The importance of mentors for growth and development (02:02:47) Key takeaways on cholesterol management and diet (02:05:13) DHA & EPA supplementation (2:08:30) Analysing cardiometabolic markers for better health (02:16:06) Outro (02:28:28) Head to the full show notes for more insights and to connect with today’s featured guests. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 30 December 2024

Episode #345. Don’t take your eyesight for granted. Join me as I sit down with optometrist Dr Joseph Allen to discover science-backed ways to care for your eyes, including common eye health myths, practical strategies for protecting your vision, and expert advice on maintaining healthy eyes for life. Learn how diet and lifestyle affect your eyesight, the truth about blue light glasses, and why regular eye exams are essential. Dr Allen also shares tips on contact lens safety, myopia prevention, and keeping your eyes healthy for years to come. Specifically, we discuss:  Introduction to Eye Health and Dr. Joseph Allen's Expertise (00:00) Dr Allen’s Journey: From Thick Glasses to Optometry Career (02:18) Busting Eye Health Myths and Misconceptions (06:25) How the Human Eye Works: Vision Explained (08:39) Top Eye Conditions: Causes, Symptoms, and Treatments (11:04) The Myopia Epidemic: Causes and Solutions (19:50) Best Practices for Maintaining Optimal Eye Health (25:12) Do Blue Light Blocking Glasses Work? A Scientific Look (33:30) The Role of Diet in Eye Health: What to Eat for Better Vision (39:52) Omega-3 Fatty Acids and Their Impact on Eye Health (46:54) Key Nutrients for Vision: Lutein, Zeaxanthin, and Leafy Greens (01:04:40) Essential Vitamins and Nutrients for Long-Term Eye Health (01:14:10) The Truth About Eye Exercises: Myths and Realities (01:21:17) Contact Lenses: Risks, Benefits, and Best Practices (01:29:16) Vision Correction Surgery: Future Trends and Options (01:33:49) Age-Related Vision Challenges: Managing Presbyopia and More (01:38:53) Expert Tips and Final Recommendations for Lifelong Eye Health (01:44:42) Learn more from Dr Joseph Allen on YouTube, and connect with him on Instagram, Facebook, or Twitter/X. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get up to 20% off plus a FREE rechargeable frother and glass beaker when you purchase exclusively at piquelife.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 23 December 2024

Episode #344. Creatine isn’t just for athletes – it’s a powerhouse supplement that benefits people of all ages and activity levels. Join me to unpack the science behind creatine and explore five evidence-based reasons why it could play a vital role in improving your health and performance. You’ll learn how creatine supports muscle strength, endurance, brain function, and even bone health. I’ll also break down dosing guidelines, clear up common misconceptions, and explore how this safe, well-studied supplement could be a game-changer for your health and performance. Specifically, we discuss: Introduction to Creatine: The Supplement Everyone Should Consider (00:00) What is Creatine? Basics, Benefits, and Origins Explained (00:56) Strength & Muscle Mass: How Creatine Amplifies Gains (03:22) Endurance & Recovery: Boost Performance with Creatine (09:24) Osteoarthritis Relief: Creatine for Joint Health and Mobility (12:56) Brain Health & Cognition: How Creatine Enhances Mental Performance (15:29) Bone Health: Strengthen Your Bones with Creatine (22:23) Choosing the Best Creatine: Types, Quality, and Recommendations (24:25) Creatine Dosage: How Much to Take for Optimal Results (28:31) Conclusion: Unlock the Full Potential of Creatine (31:08) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 19 December 2024

Episode #343. Vegan vs. carnivore – which diet stands up to the science? Join me in this fiery debate to find out. Hosted by Ellen Fisher, this thought-provoking episode pits me, Simon Hill, against Dr Robert Kiltz, a leading voice in the carnivore and keto movements. Together, we explore opposing perspectives on nutrition, from the hierarchy of evidence to the health implications of plant-based and animal-based diets. Whether you’re vegan, carnivore, or somewhere in between, this conversation will challenge your views and help you make more informed decisions about your health and the planet. Specifically, we discuss: Introduction (00:00) Personal Health Journeys: How Diet Shapes Our Lives (02:20) Scientific Evidence vs. Personal Anecdotes: Finding the Truth (07:50) Nutritional Science and Its Impact on Public Health (16:51) Mechanisms and Metabolic Health (22:55) Why Experts Disagree: Conflicting Views on Diet and Health (30:16) Ansel Keys Revisited: The Fat vs. Sugar Debate in Nutrition (54:45) Outliers in Research: How They Influence Diet Discussions (55:55) Did Humans Evolve to Eat Meat or Plants? (57:36) The Role of Fat: Separating Myths from Scientific Evidence (59:23) How Funding Influences Scientific Studies and Nutrition Advice (01:08:57) Why Dietary Guidelines Are So Complex and Confusing (01:13:17) Plant-Based vs. Carnivore: Which Diet Is Healthier? (01:18:58) Anecdotes in Nutrition: Do Personal Stories Hold Weight? (01:26:16) Diverse Perspectives: Why They Matter in Nutrition Science (01:30:44) Is There an Objective Truth in Nutrition Science? (01:46:01) Diet and Individual Truths: Why One Size Doesn’t Fit All (01:46:27) Profit Motives in Science and Medicine: What’s the Impact? (01:48:22) Processed Foods: Their Role in the Decline of Public Health (01:50:18) Health Testing: Can We Trust the Results? (01:53:03) Balancing Diet and Nutritional Freedom: Finding What Works (01:54:14) The Power of Stories: How They Shape Our Nutrition Beliefs (01:57:24) Evolutionary Diets: Do They Hold the Key to Health? (02:13:07) Ethical Diets and Planetary Health: Making Sustainable Choices (02:29:42) Final Reflections: Key Insights from the Nutrition Debate (02:33:36) Discover more of The Ellen Fisher Podcast at https://www.ellenfisher.com/podcast. Learn more about Dr Kiltz at https://www.doctorkiltz.com/blog/. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 9 December 2024

Episode #342. My all-in-one guide to nutrition: learn how to eat for health, performance, and the planet. In this special episode, I’m interviewed by Kristen Holmes, VP of Performance Science at WHOOP, for a conversation about the principles of plant-based eating and how our food choices influence long-term health and recovery. You’ll learn about the key principles of a healthy diet, the truth about protein and legumes, and the environmental impact of what’s on your plate. We also explore fascinating WHOOP data on how diet affects sleep and recovery, making this episode essential listening for anyone looking to optimise their health, performance, and wellness through nutrition. Specifically, we cover: My perspective on plant-based nutrition (00:00) Key principles of a healthy diet and debunking myths (03:29) Exploring Scientific Evidence Supporting Plant-Based Diets (13:01) How to transition to healthier dietary patterns (19:10) The truth about legumes and their nutritional value (24:17) Nutrition and protein sources in plant-based diets (31:00) Insights on sleep, recovery, and diet from Whoop data (41:16) The impact of food choices on the environment (50:24) Final thoughts and additional resources (57:03) This episode is brought to you by: 38TERA During Black Friday week get 20% off 38TERA's complete prebiotic DMN. Formulated by Dr Will Bulsiewicz and myself, DMN is the perfect way to conveniently take your gut health to the next level. Discount automatically applied at checkout at 38tera.com. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high-protein Plant Performance recipe book

Transcribed - Published: 2 December 2024

Episode #341. Confused about oils, butter, and fats in your diet? This masterclass explores which fats to prioritise, which to avoid, and how different types of fats influence your health. This episode features both a solo deep dive into the science of fats and expert contributions from past guests, offering practical tips and evidence-based guidance for smarter food choices. Joining me in this episode are world-class experts, including Dr Philip Calder, Dr Gary Fraser, Dr Gil Carvalho, Prof Roy Taylor, Dr Alan Flanagan, Dr Matthew Nagra, Dr Walter Willett, Dr Ayesha Sherzai, and Dr Dean Sherzai. Together, we unpack the science behind dietary fats and provide evidence-based insights to guide your long-term health decisions. Specifically, we discuss: Introduction (00:00) Understanding Dietary Fats: Saturated, Unsaturated, and Trans Fats (00:48) Essential vs. Non-Essential Fats (05:47) Omega-3 and Omega-6 Fatty Acids: Benefits and Sources (06:31) Brain Health and Omega-3s (07:48) Saturated vs. Unsaturated Fats and Cardiovascular Health (16:41) The Role of Omega-6 Fats in Inflammation (48:26) Insulin Resistance and Liver Fat (01:08:48) The Twin Cycle Hypothesis (01:11:04) Saturated vs. Unsaturated Fats and Fatty Liver (01:21:21) Canola Oil and Health (01:38:37) Dairy Fats and Cardiovascular Health (01:55:26) Optimising Fats in Your Diet (02:04:03) Conclusion and Recommendations (02:07:59) Head to the full show notes for additional resources and to connect with today’s guests. This episode is brought to you by: 38TERA During Black Friday week get 20% off 38TERA's complete prebiotic DMN. Formulated by Dr Will Bulsiewicz and myself, DMN is the perfect way to conveniently take your gut health to the next level. Discount automatically applied at checkout at 38tera.com. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Pique Tea Pique has unveiled its most exclusive Black Friday Cyber Monday offer ever! Get free exclusive gifts with link: piquelife.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 25 November 2024

Episode #340. Think metabolic health is all about carbs and calories? You might be missing a crucial part of the puzzle. Join me as I break down how the location and type of fat your body stores can dramatically impact your health and risk of disease. In this episode, you'll learn how body fat distribution influences your risk of metabolic disease, why weight impacts individuals differently, and how to determine if you have excess fat in your liver. Plus, discover my 6 key tips for enhancing your metabolic health through diet, exercise, and lifestyle adjustments. Specifically, we discuss: 00:00 What Is Metabolic Health and Why It Matters 00:41 The Root Cause of Poor Metabolic Health Revealed 02:55 Understanding Your Personal Fat Threshold (Key to Fat Loss) 04:32 The Twin Cycle Hypothesis: How Fat Affects Metabolism 05:10 Liver Fat: The Hidden Culprit of Metabolic Disorders 16:16 6 Proven Strategies to Reduce Ectopic & Visceral Fat 33:36 Key Takeaways: Fixing Metabolic Health in 6 Steps 35:00 Bonus Discover more insights and supporting studies in the full show notes. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link to Eimele's website for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at livemomentous.com. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF to get up to $600 off your Pod 4 Ultra purchase when bundled at eightsleep.com/theproof. This is their highest offer of the year! Try it risk-free for 30 days, with worldwide shipping. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 18 November 2024

Episode #340. Think metabolic health is all about carbs and calories? You might be missing a crucial part of the puzzle. Join me as I break down how the location and type of fat your body stores can dramatically impact your health and risk of disease. In this episode, you'll learn how body fat distribution influences your risk of metabolic disease, why weight impacts individuals differently, and how to determine if you have excess fat in your liver. Plus, discover my 6 key tips for enhancing your metabolic health through diet, exercise, and lifestyle adjustments. Specifically, we discuss: 00:00 What Is Metabolic Health and Why It Matters 00:41 The Root Cause of Poor Metabolic Health Revealed 02:55 Understanding Your Personal Fat Threshold (Key to Fat Loss) 04:32 The Twin Cycle Hypothesis: How Fat Affects Metabolism 05:10 Liver Fat: The Hidden Culprit of Metabolic Disorders 16:16 6 Proven Strategies to Reduce Ectopic & Visceral Fat 33:36 Key Takeaways: Fixing Metabolic Health in 6 Steps 35:00 Bonus Discover more insights and supporting studies in the full show notes. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link to Eimele's website for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at livemomentous.com. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF to get up to $600 off your Pod 4 Ultra purchase when bundled at eightsleep.com/theproof. This is their highest offer of the year! Try it risk-free for 30 days, with worldwide shipping. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 18 November 2024

Episode #339. Are you getting the full picture of your heart health? Learn why ApoB is the test you shouldn't skip. In this episode, I sit down with Dr Daniel Soffer, a preventive cardiologist and lipidologist, to break down the importance of ApoB testing for cardiovascular risk assessment. You'll learn why ApoB provides more comprehensive insights than LDL cholesterol alone, who can benefit most from this test, and how it fits into preventive cardiology. Dr Soffer shares practical advice for assessing cardiovascular disease risk, discusses the implications of diet and genetics on heart health, and explores case studies to help you understand when and why ApoB testing is crucial. Specifically, we discuss:  Introduction (00:00) Insight into Preventive Cardiology and Lipidology (01:38) Understanding Lipoproteins and Their Role in Cardiovascular Disease (06:40) Techniques for Lipoprotein Testing and Measurement (11:33) Exploring Atherosclerosis and Lipoprotein Retention Hypothesis (31:18) Epidemiological Changes in Health and Cardiovascular Profiles (55:06) Concerns about the Keto Diet and Elevated ApoB Levels (58:26) Approaches to Managing Elevated LDL Levels Clinically (01:01:13) The Role of Evidence-Based Medicine in Cardiovascular Guidelines (01:07:15) Comparing ApoB and LDL Cholesterol in Cardiovascular Risk (01:14:36) Understanding Discordance in Lipid Measurements (01:18:36) Advanced Imaging Techniques for Risk Assessment (01:25:50) Guidelines and Considerations for Statin Therapy (01:44:30) Coronary Artery Calcium Score, Stroke Risks, and Carotid Ultrasound (01:54:03) Dietary Interventions and Carotid Intima-Media Thickness (IMT) (01:59:22) Case Study: Family History’s Role in Cardiovascular Risk (02:05:05) Overview of Statins, PCSK9 Inhibitors, and Other Lipid-Lowering Therapies (02:12:24) Aspirin Therapy and Imaging in Cardiovascular Health (02:26:06) Setting Treatment Thresholds Based on ApoB Levels (02:39:57) Closing Thoughts on Cardiovascular Risk and ApoB (02:44:16) This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at at livemomentous.com. Pique Tea Pique’s Black Friday special is HERE. For a limited time, get a Chai tea FREE with your qualifying purchase at piquelife.com/simon. This is the only time you can get your hands on their Chai. Act fast; this limited-time offering is sure to sell out! The offer ends November 16th. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook

Transcribed - Published: 11 November 2024

Episode #338. Struggling with acne, aging, or other skin concerns? Discover how to build a science-backed skincare routine with insights from Carter “Eviba” Gottlieb. In this episode, I’m joined by Carter and special guest Tawny Janae to explore the essentials of skincare, breaking down what truly works and what might be a waste of time and money. You’ll learn about foundational skincare steps, the benefits of active ingredients like retinoids and niacinamide, and how to protect your skin from sun damage. Carter also shares tips for managing acne, avoiding common skincare myths, and building a routine that supports long-term skin health. If you’re looking to enhance your skin’s appearance and health, this episode is packed with practical, evidence-based advice. Specifically, we discuss: Introduction: Unveiling the Science of Skin Care (00:00) Carter’s Path into Dermatology and Science-Based Skincare (04:35) Carotenoids and Their Effects on Skin Health and Appearance (08:58) Debunking Myths About Supplements and Skincare (17:31) Essentials of Skin Care: Slugging, Moisturizers, and More (29:03) Retinoids Explained: Anti-Aging Powerhouses (37:31) How Exercise and Hydration Affect Skin Health (52:41) Tips for Choosing the Right Moisturizer (53:40) Understanding Skin Pigmentation and Anti-Ageing (56:38) Why Sunscreen Is the Ultimate Skin Protector (01:07:32) How to Choose the Best Sunscreen for Your Skin (01:17:58) Do Skincare Devices Really Work? (01:37:30) Gua Sha and the Benefits of Facial Massages (01:45:04) The Truth About Facials and Chemical Treatments (01:47:23) Effective Acne Treatments: Science-Backed Solutions (01:56:02) Pimple Popping: What You Should and Shouldn't Do (02:05:36) Final Thoughts on Skincare (02:14:05) Connect with Carter Gottlieb on TikTok, Instagram, YouTube, or at evibacarter.com. Connect with Tawny Janae on Instagram or YouTube, and discover 300+ classes on Alo Moves. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT – a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off all mattresses and 2 free pillows at birchliving.com/simonhill. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 4 November 2024

Episode #337. An estimated 45% of dementia cases are preventable – find out how you can reduce your risk by targeting these 14 modifiable factors. Today I’m joined by Dr Kellyann Niotis, the first fellowship-trained preventive neurologist, to explore the latest research on dementia prevention and how simple lifestyle changes can dramatically reduce your risk. In this episode, we break down The Lancet’s 14 modifiable risk factors for dementia, from managing LDL cholesterol and staying physically active to addressing hearing loss and improving your mental health. You’ll also learn about the links between nutrition, sleep, and brain health, and why it’s never too early – or too late – to start taking care of your brain. Specifically, we discuss: Introduction (00:00) Pioneering Preventive Neurology (00:07) Decoding Neurodegenerative Diseases (00:56) Understanding the Phases of Neurodegeneration (02:09) Early Indicators: Preclinical Signs and Cognitive Impairment (07:12) Uncovering Dementia’s Risk Factors and Preventive Steps (11:33) How Education Builds Cognitive Reserve Against Dementia (22:37) Why Vision and Hearing Loss Could Raise Dementia Risk (27:45) The Link Between Oral Health and Cognitive Decline (40:45) How Depression Influences Dementia Risk (52:33) Head Trauma’s Impact on Cognitive Health (59:21) How Head Injuries May Contribute to Dementia (01:01:35) How Exercise Benefits Brain Health and Longevity (01:11:43) Social Connections: A Key to Cognitive Health (01:23:56) How Diabetes Increases Dementia Risk (01:30:03) Hypertension’s Role in Cognitive Decline (01:48:00) Optimal Blood Pressure Goals for Brain Health (01:59:08) Alcohol’s Effects on Brain Function (02:01:12) Recreational Drugs and Brain Degeneration (02:09:38) Smoking’s Effect on Dementia Risk (02:12:00) The Link Between Air Pollution and Cognitive Health (02:17:49) Environmental Toxins and Dementia Risk (02:22:35) Diet Choices That May Help Prevent Dementia (02:29:30) Why Quality Sleep is Essential for Brain Health (02:35:44) Menopause’s Influence on Dementia Risk (02:46:26) Closing Thoughts and Contact Information (02:52:28) Connect with Dr Kellyann Niotis on Instagram, LinkedIn, and via her website, https://drkellyannniotis.com/. Listen to her appearance in Episode #333 here. Head to the full show notes for additional insights and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.

Transcribed - Published: 28 October 2024

Episode #336. What if our food systems could help heal the Earth? Join me as I sit down with ethnobotanist Stephen Brooks to explore permaculture, alternative living, and the future of agriculture. Together, we discuss how you can be part of the solution to building a better balance between humans and nature. You’ll learn about the principles of permaculture, the ethical issues in modern food systems, and some unique fruits to seek out. Stephen also shares his vision for designing cities and agriculture that work in harmony with the planet, and why now is the time to get involved in the transition to a healthier world. Specifically, we discuss: The World of Fruit and Plants: Connection to Nature (00:00) From Miami to Costa Rica: A Journey into Sustainability (03:59) Environmental Injustice and the Impact on Communities (05:08) Permaculture and Sustainable Agriculture Practices (11:54) How to Build Sustainable Communities through Permaculture (26:30) Perennial Vegetables: A Key to Sustainable Agriculture (39:15) Diet Trends, Agriculture, and Sustainable Living Practices (41:56) Sustainable Human Systems: Permaculture and Design (48:59) Renewable Energy Solutions for Sustainable Communities (01:16:32) Practical Urban Farming and Sustainable Practices (01:19:55) The Joy of Nitrogen-Fixing Plants and Sustainable Farming (01:30:36) Fruit Ceremonies: Building Community and Connection (01:38:30) Blueprint for Sustainable Living and Community Building (01:44:30) Connect with Stephen on Instagram, where you can find more information about his current and upcoming projects. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off all mattresses and 2 free pillows at birchliving.com/simonhill. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Transcribed - Published: 21 October 2024

Episode #335. Struggling to keep weight off long term? Learn the science behind successful fat loss and maintenance with experts Kevin Maki, PhD, and Carol Kirkpatrick, PhD. In this episode, we discuss evidence-based strategies for losing body fat and keeping it off, while exploring the role of nutrition, exercise, and pharmacological interventions. You’ll learn about the impact of protein and fibre on hunger and satiety, the benefits of regular exercise for insulin sensitivity, and the potential role of medications like GLP-1 agonists. Dr Maki and Dr Kirkpatrick also share insights on the challenges of maintaining weight loss and how to make lasting changes for better health. Specifically, we discuss: Introductions (00:00) Carol’s Journey into Nutrition and Research Development (04:27) Kevin’s Path in Cardiometabolic Health Research (11:53) The Importance of Observational Studies in Nutrition (14:59) Understanding Dietary Fats and Cardiometabolic Health (19:49) Public Health Nutrition: Current Challenges and Opportunities (31:55) Exploring Obesity and Its Impact on Metabolic Health (43:19) How Exercise Enhances Insulin Sensitivity (53:35) The Link Between Insulin Resistance and Ectopic Fat (55:01) Weight Loss Challenges: Why It’s So Hard to Keep the Weight Off (01:01:05) How GLP-1 Agonists Are Transforming Obesity Treatment (01:04:02) Behavioural Aspects of Obesity: Understanding the Psychology (01:11:22) The 30-30-30 Study: A New Approach to Sustainable Weight Loss (01:24:44) Cholesterol, Fibre, and Cardiovascular Health (01:44:02) Protein Supplements and How They Affect Digestion (01:46:56) Dietary Patterns and Regulating Appetite for Better Health (01:49:23) Exploring the 30-30-30 Framework for Weight Loss (01:51:49) How Protein Sources Influence Metabolic Health (01:57:53) Carbohydrate Quality vs. Restriction: What Matters More? (02:14:57) Exercise for Weight Maintenance and Long-term Health (02:27:12) The Future of Nutrition Research and Public Health (02:30:25) Final Thoughts (02:35:10) Connect with Kevin Maki, PhD on LinkedIn and at https://www.mbclinicalresearch.com/. Connect with Carol Kirkpatrick, PhD on Twitter/X and LinkedIn. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 15 October 2024

Episode #334. Can we turn back the clock on our biology? Join me as I sit down with Nobel Prize-winning structural biologist Dr Venki Ramakrishnan to discuss why we age, how we age, and the scientific advancements helping us live longer and healthier lives. In this episode, you'll learn about the core reasons behind aging, the role of ribosomes and DNA damage in this process, and the science behind popular longevity interventions. Dr Ramakrishnan shares his insights on misleading anti-aging claims, how much control we truly have over aging, and the truth about "biological age". We also explore practical ways to slow down aging and extend our healthspan. Specifically, we discuss: Introduction to Aging and Longevity Science (00:00) Ribosomes and Their Role in Longevity Research (00:57) Controversies in Anti-Aging Research (05:09) Understanding the Biology of Aging (11:25) Genetics and Evolution: How They Shape Human Lifespan (22:10) Youthful Cells: The Future of Longevity Studies (29:38) Biological Interventions in Aging: Potential and Risks (46:09) Ancestral Living and Traditional Medicine for Longevity (52:09) Cellular Aging Mechanisms: A Deeper Look (56:51) Protein Synthesis and Its Impact on Aging Processes (01:04:19) DNA Damage and Repair: Implications for Aging (01:16:53) Lifestyle Choices That Influence Aging and Lifespan (01:24:03) Philosophical Perspectives on Extended Human Longevity (01:32:53) Concluding Thoughts on Aging and Longevity Research (01:43:21) Learn more about Dr Venki Ramakrishnan here, and be sure to check out his books Gene Machine and Why We Die. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 7 October 2024

Episode #333. What does cholesterol have to do with dementia? Learn how to protect your brain health in the long term with this information you should be considering from your twenties and thirties. From cutting-edge science on cholesterol metabolism to fourteen key risk factors for dementia, we break down what you can do now to reduce your risk of cognitive decline later. In this episode, I’m joined by two renowned experts, Dr Kellyann Niotis and Dr Thomas Dayspring. Together, we explore the connection between cholesterol and dementia, personalised prevention strategies, and how making lifestyle changes today can safeguard your brain for the future. Specifically, we discuss: Intro (00:00) Cardiology Meets Neurology: Understanding the Connection (07:53) Dementia and Neurodegenerative Diseases: A Comprehensive Overview (13:26) Recognizing Early Dementia Signs and Risk Factors (21:43) Lipoproteins and Brain Health: The Crucial Link (32:36) ApoB vs ApoE: Comparing Apoprotein Functions in Neurological Health (44:24) APOE4 Carriers: Potential Therapeutic Approaches (01:00:30) ApoA1 and HDL: Their Role in Dementia Prevention (01:03:27) Genetic Testing for Dementia: Understanding APOE4 Implications (01:13:19) APOE4 Gene: Impact on Dementia Risk and Brain Health (01:17:58) Desmosterol's Role in Maintaining Brain Health (01:20:56) LDL Cholesterol: A Key Factor in Dementia Risk Assessment (01:34:05) APOE4: Comparing Single vs. Double Copy Risk Factors (01:39:15) Omega-3 Fatty Acids: Essential Nutrients for Brain Health (01:38:49) LDL Cholesterol Levels: Assessing Low vs. High Risk for Dementia (01:56:50) Key Takeaways: Preventive Neurology and Future Research Directions (02:00:10) Connect with Dr Kellyann Niotis at https://drkellyannniotis.com/ and discover research and resources at https://ind.org/. Connect with Dr Thomas Dayspring on Twitter/X or LinkedIn, and listen to his past appearances on The Proof here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Transcribed - Published: 30 September 2024

Episode #332. Blood tests can be confusing, but they don’t have to be. Learn how to interpret your comprehensive blood test results as I walk through key markers for cardiometabolic, hormonal, and overall health. Discover why I recommend blood tests every 6–12 months, learn the results of my most recent blood test, and hear insights from esteemed scientists Dr Thomas Dayspring and Dr Karl Nadolsky in this thorough guide. Specifically, I cover: Introduction (00:00) Personal Health Journey and Lifestyle Context (04:06) Cardiometabolic Biomarkers: Cholesterol, Triglycerides, and ApoB (09:29) Debunking the Triglycerides-to-HDL Ratio Debate (20:56) Insulin Sensitivity and Metabolic Health Markers (29:10) Hormones: Testosterone Levels and Testing (30:42) Thyroid Function: Family History and Test Interpretation (37:19) Iron and Micronutrient Insights (50:12) Key Lifestyle Habits for Optimal Health and Final Thoughts (51:44) Download my full blood test results here, or head to the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 23 September 2024

Episode #332. Blood tests can be confusing, but they don’t have to be. Learn how to interpret your comprehensive blood test results as I walk through key markers for cardiometabolic, hormonal, and overall health. Discover why I recommend blood tests every 6–12 months, learn the results of my most recent blood test, and hear insights from esteemed scientists Dr Thomas Dayspring and Dr Karl Nadolsky in this thorough guide. Specifically, I cover: Introduction (00:00) Personal Health Journey and Lifestyle Context (04:06) Cardiometabolic Biomarkers: Cholesterol, Triglycerides, and ApoB (09:29) Debunking the Triglycerides-to-HDL Ratio Debate (20:56) Insulin Sensitivity and Metabolic Health Markers (29:10) Hormones: Testosterone Levels and Testing (30:42) Thyroid Function: Family History and Test Interpretation (37:19) Iron and Micronutrient Insights (50:12) Key Lifestyle Habits for Optimal Health and Final Thoughts (51:44) Download my full blood test results here, or head to the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 23 September 2024

Episode #331. Are you getting the right balance of omega-3 and omega-6 fats in your diet? Join me as I sit down with leading scientists to explore the role these essential fatty acids play in your health. From brain development and cognitive function to heart health and inflammation, we unpack how these fats impact your well-being and address common misconceptions about omega-6 fats. You’ll hear from top voices in nutrition, including Dr Bill Harris, Dr Joel Fuhrman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Gary Fraser, Dr Phillip Calder, and Dr Kristina Harris. Each expert shares valuable insights into how omega-3s and omega-6s influence everything from cognitive function to heart disease. We cover: Introduction to Omega-3 and Omega-6 Fatty Acids (00:00) What is Omega-6 and Why the Body Needs It (01:06) What is Omega-3 and Do We Really Need It? (12:29) The Importance of Optimising Omega-3 Consumption (42:50) Understanding DHA and EPA: Why Are They Essential? (50:01) Are Omega-3s the Most Important Fatty Acids for Brain Health? (55:44) APOE4 and Omega-3 Supplementation: What You Need to Know (1:08:50) Low Omega-3 Index and Neurological Problems in Seventh-day Adventist Church Members (1:15:00) Omega-3 Supplementation vs Fatty Fish: What Does Research Indicate? (1:21:53) Understanding Essential Fats: Benefits and Sources (1:27:25) Low Conversion Rates: From ALA to EPA & DHA Explained (1:31:39) The Importance of Monitoring Omega-6 Intake (1:37:03) The Link Between Omega-6 Fatty Acids and Inflammation (1:40:55) Major Omega-6 Food Sources and Healthier Alternatives (1:45:45) Balancing Omega-3 & Omega-6 to Reduce Inflammation (1:50:25) The Health Implications of Replacing Saturated Fat with Linoleic Acid (1:53:48) Polyunsaturated Fats and Cardiometabolic Health (1:58:19) How Omega-3 & Omega-6 Influence Insulin Resistance and Blood Pressure (2:01:44) The Long-Term Impact of Consuming Polyunsaturated Fats (2:06:32) Why You Should Measure Your Omega-3 Levels (2:10:07) DHA and EPA: Food Sources and Effective Supplementation (2:14:20) What Forms of DHA and EPA Supplementation Are Most Effective? (2:18:37) How to Properly Store DHA and EPA Supplements (2:20:27) Pregnancy and Omega-3s: Essential Benefits (2:21:33) Supplementing Omega-3s During Pregnancy: Guidelines (2:29:55) Omega-3 Supplementation Protocol: A Comprehensive Guide (2:38:16) Outro (2:52:15) Thank you for tuning in, and for your ongoing commitment to your health. If you found this episode helpful, please share it with someone who could benefit from it. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Transcribed - Published: 16 September 2024

Episode #330. Uncover the key foundations of a healthy diet and learn how to reduce your risk of chronic disease. What does it take to truly eat well? How do you stay healthy in a food system that prioritises profit? In this episode, originally recorded for Sigma Nutrition Radio, I answer these questions and more. Learn practical, science-based strategies for building healthier eating habits that can have a lasting impact on your well-being. Tune in to explore topics like nutrition, chronic disease prevention, and how to make informed dietary choices for better long-term health. Specifically, we discuss: Introduction (00:00) Simon’s Background and Journey into Nutrition Science (01:26) The Importance of Science and Objectivity in Nutrition Advice (08:38) Barriers to Healthy Eating and Population-Level Solutions (16:06) Challenges of Adopting Plant-Based Diets and Solutions (30:38) Omega-3 Fatty Acids: Health Benefits and Plant-Based Sources (38:17) Conclusion and Final Thoughts on Nutrition and Health (47:21) This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 9 September 2024

Episode #329. Boost metabolic health and prevent disease with expert insights from an all-star lineup of scientists. Learn key strategies for improving metabolic health, including metabolic flexibility, muscle health, and the critical roles of diet and exercise in preventing type 2 diabetes and fatty liver disease. In this episode, you’ll hear from a distinguished panel of specialists including applied exercise physiologist Inigo San Millan, PhD; skeletal muscle expert Don Layman, PhD; type 2 diabetes authority Roy Taylor, PhD; dietitian and researcher Andrea Glenn, PhD, RD; nutrition scientist Alan Flanagan, PhD; nutrition scientist and endocrinologist Christos Mantzoros MD, DSc, PhD; and physician and researcher Richard Johnson, MD. Specifically, we discuss: Intro (00:00) What is Metabolic Health (01:35) Metabolic Health, Mitochondria, Defining 'Metabolise', Metabolic Flexibility (07:02) The Importance of Skeletal Muscle for Metabolic Health (20:03) Exercise for metabolic health ****Zone 2 (28:36) Twin Cycle Hypothesis (56:45) Understanding the Personal Fat Threshold (01:08:15) Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor (01:17:08) Are DASH, Nordic, Mediterranean, and Portfolio diets good for preventing and managing diabetes? (01:36:46) Understanding Non-Alcoholic Fatty Liver Disease and Its Development (01:42:39) The Science of Hepatic Fat Oxidation (01:49:37) Consequences and Effects of Fatty Liver Disease (01:55:14) Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (02:00:42) Combination of Fructose and Saturated fat on Metabolic Health (02:13:21) Type of fat and its effect on Metabolic Health (02:17:35) What cause Metabolic Health: fat or fructose (02:24:01) New Fat Storage Mechanisms - Personal Fat Threshold (02:27:50) Modern Techniques for Accurate Body Fat Measurement (02:31:52) Health metabolic biomarkers (02:36:51) Ectopic fat (02:38:19) Fat storage and metabolic health (02:39:10) Evolutionary Insights into Human Fat Storage (02:42:02) Fatty Liver Disease (02:45:46) Outro (2:57:46) Connect with today’s guests and listen to their previous episodes at the links above. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high-protein Plant Performance recipe book

Transcribed - Published: 2 September 2024

Episode #328. Are eggs a superfood or a ticking time bomb? The answer is in your genes. Join me to unpack the surprising science of how eggs affect your health depending on your genetic makeup, helping you understand if they’re safe for you. Discover the two tests you can take to find out if you’re among the 30% of people who are cholesterol hyper-absorbers. You’ll also learn the difference between dietary and blood cholesterol, why cholesterol absorption varies, and what steps to take based on your test results. Specifically, we discuss: Introduction: Are Eggs Superfoods or Cholesterol Bombs? (00:00) Understanding Cholesterol: Dietary vs. Blood Levels (01:25) The Genetic Factors Influencing Cholesterol Absorption (04:31) Identifying Cholesterol Hyperabsorbers: Are You One? (09:20) Testing Methods for Cholesterol Sensitivity (12:41) Dietary Tips for Cholesterol Hyperabsorbers (13:59) Key Insights: 5 Critical Facts About Eggs and Heart Health (18:06) Concluding Thoughts (21:23) Head to the full show notes for supporting studies and phytosterol testing options. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 26 August 2024

Episode #327. Butter, bone broth, and eating like our ancestors: join me on The Ellen Fisher Podcast to bust some prolific nutrition myths. Tune in to unpack my core nutrition philosophy, evaluate how popular diets can impact your health, and examine some key foods that are either idolised as superfoods or condemned as dangerous. If you have questions about keto, carnivore, antinutrients, or other hot nutrition topics, this episode is for you. Specifically, we discuss: Introduction (00:00) Exploring Personal Nutritional Philosophy (02:31) Science's Role in Nutritional Understanding (06:33) Integrating Science and Nature in Dietary Patterns (10:55) Ancestral Diets Explained (14:40) Saturated Fats and ApoB: Their Crucial Role in Diet (21:03) Strategies for Reducing Saturated Fat and ApoB Levels (26:49) Analyzing Evidence Against Saturated Fat Claims (30:16) Polyunsaturated Fats: Health Impacts Unveiled (40:13) Processed Foods and Overconsumption Risks (47:33) Butter and Saturated Fats: Revealing the True Health Effects (49:26) Comparative Analysis of Various Diets and Health Outcomes (53:30) Debunking Anti-Nutrient Myths (01:04:36) Debating Contrasting Nutritional Perspectives with Paul Saladino (01:16:07) Saturated Fats Comparison: Coconut vs. Red Meat (01:22:26) The Importance of Personal Health Metrics (01:25:15) Evaluating Plant Milks and Processed Food Alternatives (01:29:26) Beef Liver Consumption and Nutrient Toxicity Risks (01:31:15) Critiquing Vegan Diets and Low-Fat Diet Misconceptions (01:36:54) Holistic Health and Longevity: Defining the Ultimate Goal (01:45:32) Conclusion and Key Takeaways (01:48:07) Discover more of the Ellen Fisher podcast at https://www.ellenfisher.com/podcast, or listen to her previous appearance on The Proof. Visit the full show notes for more insights and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 19 August 2024

Episode #327. Butter, bone broth, and eating like our ancestors: join me on The Ellen Fisher Podcast to bust some prolific nutrition myths. Tune in to unpack my core nutrition philosophy, evaluate how popular diets can impact your health, and examine some key foods that are either idolised as superfoods or condemned as dangerous. If you have questions about keto, carnivore, antinutrients, or other hot nutrition topics, this episode is for you. Specifically, we discuss: Introduction (00:00) Exploring Personal Nutritional Philosophy (02:31) Science's Role in Nutritional Understanding (06:33) Integrating Science and Nature in Dietary Patterns (10:55) Ancestral Diets Explained (14:40) Saturated Fats and ApoB: Their Crucial Role in Diet (21:03) Strategies for Reducing Saturated Fat and ApoB Levels (26:49) Analyzing Evidence Against Saturated Fat Claims (30:16) Polyunsaturated Fats: Health Impacts Unveiled (40:13) Processed Foods and Overconsumption Risks (47:33) Butter and Saturated Fats: Revealing the True Health Effects (49:26) Comparative Analysis of Various Diets and Health Outcomes (53:30) Debunking Anti-Nutrient Myths (01:04:36) Debating Contrasting Nutritional Perspectives with Paul Saladino (01:16:07) Saturated Fats Comparison: Coconut vs. Red Meat (01:22:26) The Importance of Personal Health Metrics (01:25:15) Evaluating Plant Milks and Processed Food Alternatives (01:29:26) Beef Liver Consumption and Nutrient Toxicity Risks (01:31:15) Critiquing Vegan Diets and Low-Fat Diet Misconceptions (01:36:54) Holistic Health and Longevity: Defining the Ultimate Goal (01:45:32) Conclusion and Key Takeaways (01:48:07) Discover more of the Ellen Fisher podcast at https://www.ellenfisher.com/podcast, or listen to her previous appearance on The Proof. Visit the full show notes for more insights and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 19 August 2024

Episode #326. Could the oils you’re using in the kitchen be increasing your risk of chronic disease? Explore the essential facts about dietary fats and how they affect your health markers in this focused deep dive. Learn which oils to eat and avoid, how to adjust your diet for optimal intake, and how fats can make the difference between health and chronic disease. Specifically, I cover: Introduction to Dietary Fats (00:00) Types of Fats Explained (02:27) Essential vs. Non-Essential Fats - What's the Difference? (07:54) Fats and Cardiovascular Health - Unveiling the Connection (10:32) How Dietary Fats Influence Blood Pressure (17:47) The Fat-Inflammation Link (20:29) Exploring the Relationship Between Fats and Insulin Resistance (26:03) Long-Term Health Outcomes of Dietary Fat Consumption (29:51) Optimising Fat Intake: Practical Dietary Recommendations (36:22) Wrapping up and Final Thoughts (41:25) Head to the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 13 August 2024

Episode #325. Fish oil supplements: harmful or heart-healthy? Learn about the risks and benefits of omega-3 supplementation, including an analysis of a new study that’s been making waves. Discover how to test your omega-3 levels, how to achieve the optimal index, and my supplement recommendations for a healthy heart and planet. Specifically, I cover: Introduction to Omega-3 Fatty Acids and Fish Oil Supplements (00:00) New Research Reveals Fish Oil's Impact on Cardiovascular Health (01:03) Challenging Assumptions - A Different Take on the Fish Oil Study Results (05:14) Dr. Bill Harris Weighs In - Expert Opinions on Omega-3 Benefits (09:03) How Can I Increase My Omega-3 Levels? Practical Advice for Everyday Life (17:26) Omega-3 Supplement Strategy (18:50) Comparing Sustainable Omega-3 Sources: Algae Oil vs. Fish Oil (24:05) How much omega-3 is too much (25:58) Does the form of DHA and EPA matter? (28:00) Does EPA DHA ratio matter? (28:44) Omega-3 Supplementation for Vegans and Vegetarians (31:50) Key Takeaways and Recommendations for Omega-3 Supplementation (35:55) Head to the full show notes for additional insights and supporting resources. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 6 August 2024

Episode #324. A crash course for carnivores: let’s talk saturated fat, heart disease, and protein as I’m interviewed on Mark Bell’s Power Project. Do you need to change your diet if you’re feeling good? Can you be overweight and healthy? What simple changes can meat eaters make to improve their long-term health? Hear my answers to these questions and more in this episode. We cover: Introduction and Podcast Overview (0:00) Finding Common Ground in Nutritional Science (02:15) Genetic Testing and Personalised Nutrition (06:48) Heart Health Unveiled: The Saturated Fat and ApoB Connection (10:40) Nutritional Strategies vs Medication for Lowering ApoB (18:39) Understanding Epidemiology Studies on Red Meat (27:07) Practical Tips for Transitioning from Animal to Plant Protein (42:05) A Personal Journey with Nutrition (48:53) Weight Loss and Metabolic Health Insights (53:41) Exploring Health Impacts of an All-Meat Diet (01:02:59) Comparing Plant and Animal Protein Bioavailability (01:12:13) The Role of Protein in Satiety (01:16:44) Addressing Seed Oils (01:20:16) Incorporating Vegetables and Plant Proteins for Optimal Health(01:27:30) Carnivore Diet vs Plant-Based Diet Discussion (01:33:34) The Undeniable Importance of Resistance Training (01:39:13) Ensuring Adequate Intake for Thyroid Health (01:47:23) Final Thoughts and Farewell (01:50:12) In this episode, we discuss the importance of getting regular blood tests. Download my free blood test guide to get started. Connect with Mark Bell, Nsima Inyang, and Andrew Zaragoza on Instagram. If you’re interested in hearing more of Mark Bell’s Power Project, head to https://powerproject.live/. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 29 July 2024

Episode #323. Oreo cookies or statins – which is more effective in reducing LDL cholesterol? The results from one study might surprise you. Join me as I sit down with Oxford PhD graduate and Harvard Medical student Dr Nick Norwitz to discuss the lipid energy model, what it has to do with Oreos, and how different diets affect your health. You’ll learn about Dr Norwtiz’s health journey, including his experience with inflammatory bowel disease and the ketogenic diet. We discuss cholesterol management and cardiovascular disease risk, lean mass hyper-responders, and statins. This episode is an important and informative reflection on scientific curiosity and misinformation. Specifically, we discuss: Introduction (00:00:00) The Importance of Curiosity in Scientific Progress (04:39) Exploring the Oreo vs. Statin Experiment on Lean Mass Hyper Responders (08:52) Scientific and Clinical Impact of the Oreo Study (25:03) Addressing Criticisms and Misinterpretations of the Study (34:47) Navigating Statin Discussions on Social Media (40:27) Debunking Claims About PCSK9 Inhibitors (53:18) Challenging Misinformation in Health Communities (59:15) The Lipid Energy Model and Lean Mass Hyper Responders Explained (01:06:59) Defining Lean Mass Hyper Responders: Key Terminology (01:14:19) Practical Advice for Lean Mass Hyper Responders (01:30:35) The Carnivore Kid: An Intriguing Case Study (01:41:48) Personal Struggles with Ulcerative Colitis and Starting Keto (01:45:24) Balancing Medication and Personal Health Choices (01:50:31) Debating Dietary Interventions for Inflammatory Bowel Disease (02:11:09) Challenges in Dietary Research and Medical Interventions (02:25:55) Introducing the Lipid Energy Model and Its Mechanisms (02:34:49) Debating the Validity of the Lipid Energy Model (02:44:29) Long-Term Effects of Ketosis and Carb Restriction (02:52:31) Critiques and Limitations of the Lipid Energy Model (02:57:17) ApoB-Containing Lipoproteins and Atherosclerosis (03:03:50) Current Research and Future Directions on LMHR (03:06:41) Exploring Inflammatory Responses to Fibre (03:16:12) The Link Between Saturated Fats and Heart Disease (03:20:49) Closing Thoughts on Effective Scientific Communication (03:25:29) The Lean Mass Hyper Responders Debate: Addressing Frustrations (03:32:32) Understanding Carbohydrate Reintroduction Physiology (03:46:58) Diet-Specific Strategies to Lower ApoB (03:55:16) Examining Claims About ApoB and Cardiovascular Disease (04:01:50) Trade-offs in Lowering ApoB Levels (04:12:54) Exploring the Link Between All-Cause Mortality and ApoB (04:22:42) Lean Mass Hyper Responders and ApoB: A Unique Profile (04:44:54) Concluding Thoughts and Future Discussion Topics (04:48:10) Connect with Nick Norwitz, PhD on Twitter/X, Instagram, and YouTube. Make sure to check out the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill

Transcribed - Published: 23 July 2024

Episode #322. Did you know that 30% of cancers are related to obesity? Join me as I sit down with Harvard Professor and endocrinologist Dr Christos Mantzoroz to discuss fatty liver disease, metabolic health, and hormones. You’ll learn about why so many people are obese and whether you can be overweight and healthy. Dr Mantzoroz breaks down budget-friendly ways to evaluate your metabolic health, explains how hormones affect your weight, and offers his insight on how to treat obesity. Overall, this episode is a masterclass in metabolic health and fatty liver disease. Specifically, we discuss: Introduction to The Latest Obesity Research Findings (00:00) The Evolving Understanding of Obesity Science (03:49) Uncovering New Fat Storage Mechanisms (10:57) Modern Techniques for Accurate Body Fat Measurement (15:02) Why Maintaining Weight Loss Is So Challenging (20:01) Evolutionary Insights into Human Fat Storage (25:12) How Leptin Regulates Energy Balance and Health (29:17) New Approaches to Break Through Weight Set Points (39:27) Environment's Role in Weight Gain Beyond Diet (45:49) Decoding the Genetics of Fat Storage and Metabolism (52:59) Non-Alcoholic Fatty Liver Disease Explained (55:40) Evidence-Based Nutrition for Optimal Liver Health (01:05:25) Promising Advances in Non-Invasive Liver Tests (01:10:49) Oestrogen's Impact on Metabolism (01:20:14) The Link Between Liver Fat and Insulin Resistance (01:22:04) Addressing America's Growing Metabolic Health Crisis (01:26:11) Outro (01:27:11) Connect with Christos Mantzoros, MD DSc PhD h.c. mult. on LinkedIn, and discover his work here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 15 July 2024

Episode #322. Did you know that 30% of cancers are related to obesity? Join me as I sit down with Harvard Professor and endocrinologist Dr Christos Mantzoroz to discuss fatty liver disease, metabolic health, and hormones. You’ll learn about why so many people are obese and whether you can be overweight and healthy. Dr Mantzoroz breaks down budget-friendly ways to evaluate your metabolic health, explains how hormones affect your weight, and offers his insight on how to treat obesity. Overall, this episode is a masterclass in metabolic health and fatty liver disease. Specifically, we discuss: Introduction to The Latest Obesity Research Findings (00:00) The Evolving Understanding of Obesity Science (03:49) Uncovering New Fat Storage Mechanisms (10:57) Modern Techniques for Accurate Body Fat Measurement (15:02) Why Maintaining Weight Loss Is So Challenging (20:01) Evolutionary Insights into Human Fat Storage (25:12) How Leptin Regulates Energy Balance and Health (29:17) New Approaches to Break Through Weight Set Points (39:27) Environment's Role in Weight Gain Beyond Diet (45:49) Decoding the Genetics of Fat Storage and Metabolism (52:59) Non-Alcoholic Fatty Liver Disease Explained (55:40) Evidence-Based Nutrition for Optimal Liver Health (01:05:25) Promising Advances in Non-Invasive Liver Tests (01:10:49) Oestrogen's Impact on Metabolism (01:20:14) The Link Between Liver Fat and Insulin Resistance (01:22:04) Addressing America's Growing Metabolic Health Crisis (01:26:11) Outro (01:27:11) Connect with Christos Mantzoros, MD DSc PhD h.c. mult. on LinkedIn, and discover his work here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 15 July 2024

Episode #321. You’ve heard me interview hundreds of nutrition experts; now it’s time for me to share my comprehensive views on nutrition, health, and longevity. Join me as I’m interviewed by André Duqum in this conversation originally recorded for the Know Thyself podcast. This episode covers the foundations of healthy eating and my take on common nutrition controversies. You’ll learn how to decode health information you find online, why a plant-focused diet is the best way forward, and how to discover the optimal diet for you. Overall, we discuss what to eat and avoid, when to eat, and how your food choices impact your body and the planet. Specifically, we discuss: Understanding Nutrition Science (04:07) The Role of Observational Studies in Nutrition (09:18) What Is the Most Beneficial Diet for Humans? (13:12) Simon Hill's Personal Journey and Motivation (19:38) Five Pillars of Longevity (27:50) Importance of Protein in the Diet (31:27) Understanding Seed Oils and Polyunsaturated Fats (50:23) Importance of Fibre in the Diet (58:32) Choosing the Best Animal Proteins (01:10:06) Role of Fake Meats in a Plant-Based Diet (01:14:52) Metabolic Health and Dietary Fats (01:19:40) Supplementation and Nutrient Gaps (01:24:22) Debunking Myths About Anti-Nutrients in Plants (01:30:20) The Soy Controversy Explained (01:38:20) Challenges of Plant-Based Diets (01:41:29) Environmental Impact of Diet Choices (01:59:04) Optimising Meal Timing (02:07:07) Importance of Relationships for Longevity (02:12:52) Connect with André Duqum on Instagram, and discover the Know Thyself podcast on Instagram or at the official website, https://www.knowthyself.one/. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 8 July 2024

Episode #320. Are you part of the 20% of people with this dangerous gene? There’s a cheap, simple test you can do just once in your life to find out. Join me as I sit down with renowned lipidologist Dr Thomas Dayspring to help you understand Lipoprotein(a) and the test that might change your life. In this episode, you’ll learn what Lp(a) is and how it can affect your cardiovascular disease risk through two key pathways. Dr Dayspring unpacks why it’s so important to test, how to ask for this test, and what to do with your results. Specifically, we discuss: Introduction (00:00) Demystifying Lipoprotein(a): An Overview of its Role in Cardiovascular Health (02:54) Genetic Inheritance Patterns and Variability of Lipoprotein(a) (10:11) Drug Development Strategies for Reducing Lipoprotein(a) Levels (14:50) Exploring the Functional Role and Genetic Variations of Lipoprotein(a) (20:27) Inside the Artery Walls: Mechanisms and Structure of Lipoprotein(a) (32:34) A Deep Dive in Production to Measurement of Lipoprotein(a) (42:32) Identifying High-Risk Indicators for Lipoprotein(a) (58:54) Statins and Elevated Lipoprotein(a): Understanding the Relationship (01:11:42) Exploring PCSK9 Inhibitors in Lipoprotein(a) Management (01:20:30) Emerging Treatments and Future Therapies for Lowering Lipoprotein(a) (01:31:22) Exploring Lifestyle Considerations and Alternative Therapies (01:34:42) Oxidized Phospholipids and Their Role in Cardiovascular Health (01:43:15) Relationship Between Oxidized Phospholipids and Lipoprotein(a) (01:52:00) Understanding Aortic Valve Calcification and Its Link to Lipoprotein(a) (01:59:40) Key Takeaways and Future Landscape of Lipoprotein(a) Treatments (02:06:52) Conclusion and Final Remarks (02:13:30) Connect with Dr Thomas Dayspring on Twitter/X. Listen to our previous lipid series and download the cheat sheet here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 1 July 2024

Episode #319. Join me today as I sit down with a very special guest: my dad, Professor Michael Hill, PhD. Dad’s journey as a scientist has inspired my own work and taken our family across the globe, and I’m honoured to host him as he shares his story from early career discoveries to current research. As well as getting an inside look at Dr Hill’s academic career, you’ll learn about microvasculature (very small blood vessels), including what they are and how they impact human health. Dad also shares his experience with a heart attack, offers advice on preventing atherosclerosis, and weighs in on the Ozempic and vaping conversations. Specifically, we discuss: Introduction (00:00) Childhood Memories and Early Interests (03:19) Pursuing a Career in Biochemistry (08:36) Microvasculature and Diabetes Research (12:12) Early Research on Investigating Blood Properties and Diabetes (17:44) Family Stories and Moving to the U.S. (28:47) Returning to Australia and Continued Research (36:39) Exploring Microvessel Behaviours: Research at RMIT (41:34) Dealing with Health Challenges and Maintaining Work-Life Balance (46:20) Understanding Microvascular Functions and Cardiac Health (50:32) Exploring Vessel Constriction and Small Blockages: A Closer Look (01:00:15) Understanding the Impact of Large Arterial Stiffness on Vascular Health (01:07:01) Identifying Risk Factors: A Comprehensive Approach to Vascular Well-being (01:11:01) Personal Views on the Evolution of Scientific Research Access (01:19:39) Returning to the USA: Advancing Research on Blood Vessel Mechanisms (01:21:58) COVID-19 and Metabolic Syndromes: Exploring the Early Research Connections (01:27:30) Current Research and Future Directions (01:29:29) Reflecting on a Career Dedicated to Science: Family, Achievements, and Future Directions (01:34:48) If you’re interested in learning more about Dad’s work and career, head to his profile here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Transcribed - Published: 24 June 2024

Episode #318. 50,000 women. 30 years of follow-up. The results of a new study are in: learn the truth about how your protein intake will affect your long-term health. What kind of protein should you consume? How much? And what difference will it really make on longevity? Today, I’m unpacking the results from the new study in the American Journal of Clinical Nutrition, “Dietary protein intake in midlife in relation to healthy aging - results from prospective Nurses' Health Study cohort”. This new study from researchers at Harvard University and Tufts University has been regularly misinterpreted online, and in this episode, I’ll set the facts straight. Learn the three most important protein takeaways from this study, hear my take on Layne Norton’s interpretation, and crack the code to using protein as a tool for healthy aging. Specifically, I cover: Introduction to Protein and Longevity (00:00) Study Overview and Methodology (01:24) Key Findings on Protein Sources (05:33) Lane Norton's Review and Critique (06:38) Analysis of Different Protein Types (10:02) Practical Recommendations for Protein Intake (17:13) Conclusion and Final Thoughts (21:34) If you’re interested in the Danish Dietary Guidelines, you can find them in English here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcribed - Published: 17 June 2024