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BBC Inside Science

Neanderthals; Plague; Wind Tunnel; Music Timing; Stem Cells

BBC Inside Science

BBC

Technology, Science

4.51.3K Ratings

🗓️ 30 January 2014

⏱️ 29 minutes

🧾️ Download transcript

Summary

We now know that Neanderthals and our ancestors interbred over 40,000 years ago. Recent research has shown that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. But two new papers this week examine some of the physical characteristics we may have got from the genes of our ancient cousins. They include some disease susceptibilities and hair and skin characteristics, which may have helped our forebears survive in northern climes.

There have been many sensationalist headlines in the news this week suggesting that the deadly bubonic plague could return, when really, it never went away. And while it can still be deadly, it can be treated early with antibiotics. In the Middle Ages the Black Death is thought to have killed up to half of the European population and so too did the Justinian Plague 800 years earlier. Now scientists have compared these two plague genomes to find that they were both caused by distinct strains of the same bacterium, Yersinia Pestis. Knowing how the pathogen evolved in the past is crucial to our understanding of possible future strains of plague. Lead author Dr David Wagner from the University of Arizona tells Dr Adam Rutherford that it's very unlikely the plague will return on a mass scale.

It's a windy Show Us Your Instrument this week - Prof Konstantinos ('Kostas') Kontis, Professor of Aerospace Engineering shows us around his wind tunnel. It's used to help develop more effective plane wings, helicopter rotors, and wind turbine blades, but cyclist Sir Chris Hoy has also been a test sample. Glasgow University is currently building a hypersonic wind tunnel, which can test air flow at speeds of up to Mach 10.

We all unconsciously synchronise our movements and researchers at the University of Birmingham have shown how professional musicians make tiny adjustments in their playing to keep time with their colleagues. Alan Wing, Professor of Human Movement in Psychology tells Adam how this research about minute synchronisation is helping to inform how robots can be designed to interact with humans.

Stem cells can become any other cell in the body from nerve to bone to skin, and they are touted as the future of medicine. Embryos are one, often ethically charged, source of stem cells and in 2006 Nobel prize winning research showed that skin cells could be "genetically reprogrammed" to become stem cells. These were called induced pluripotent stem cells. Scientists in Japan have now shown, in mice, that this previous painstaking method of making the versatile cells can be replaced by little more than a short dip in acid. Professor Chris Mason from University College London tells Adam that this major breakthrough could be faster, cheaper and possibly safer than other cell reprogramming technologies.

Producer: Fiona Hill.

Transcript

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0:00.0

Just before this BBC podcast gets underway, here's something you may not know.

0:04.7

My name's Linda Davies and I Commission Podcasts for BBC Sounds.

0:08.5

As you'd expect, at the BBC we make podcasts of the very highest quality featuring the most knowledgeable experts and genuinely engaging voices.

0:18.0

What you may not know is that the BBC makes podcasts about all kinds of things like pop stars,

0:24.6

poltergeist, cricket, and conspiracy theories and that's just a few examples.

0:29.7

If you, I'm

0:34.3

I'm at something a little bit unexpected, find your next podcast over at BBC Sounds.

0:36.9

Hello you, I'm Adam Rutherford and this is the BBC Inside Science Podcast first

0:41.0

broadcast on the 30th of January.

0:43.5

On this day in 1661, Oliver Cromwell was executed, and in 1941, Dick Cheney was born.

0:50.1

Coincidence, yes, and crucially nothing to do with the programme.

0:53.3

Terms and conditions at BBC.co. UK slash Radio 4.

0:57.2

This week, imperceptible adjustments in timing from professional performers were turning skin cells into stem cells, no high-tech genetics, but an acid

1:05.7

bath about as strong as French mustard.

1:08.6

Our instrument of the week really sucks and blows, it's a wind tunnel, and forget the black death the Romans were struck hard by the Justinian

1:16.2

plague and upon opening some of the swellings they found a strange sort of carbuckle that had grown inside them.

1:24.0

By Tutatis, sixth century historian Procopius on the plague that ravaged the classical world,

1:29.7

now rediscovered from ancient DNA, but will we see it return? First, with those advances in

1:35.5

digging out the DNA of long dead souls, we can piece back together stories not

1:40.1

just from history, but from prehistory. We've assembled the whole genome of the Neanderthals

1:45.2

from bones more than 40,000 years old and we're finally in a position to ask

1:50.4

what did the Neanderthals ever do for us?

...

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