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Mark Bell's Power Project

Peptide Therapeutics: The Role of GLP-1 in Fitness and Weight Loss - Justin Kirkland || MBPP Ep. 1133

Mark Bell's Power Project

Power Project Studios

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4.81.6K Ratings

🗓️ 24 March 2025

⏱️ 110 minutes

🧾️ Download transcript

Summary

What if optimizing your fitness and losing weight came down to peptides? In episode 1133 of Mark Bell’s Power Project Podcast, Mark Bell, Nsima Inyang, and Justin Kirkland discuss how GLP-1 peptides are transforming fitness and health. Justin explains, “It’s not just about the weight loss—it’s about using these compounds as tools for long-term lifestyle changes.”


Learn how GLP-1 curbs cravings, supports better eating habits, and the science behind delivery methods like advanced coatings for oral absorption versus injectables. They also dive into maintaining muscle while shedding fat with strategies like resistance training and mindful nutrition.


Packed with insights on peptide innovation and safe usage, this episode is a must-watch for anyone dedicated to health, fitness, and personal growth. Don’t miss the conversation on using peptides to unlock better results while tackling challenges like muscle mass loss and dosage management!


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Transcript

Click on a timestamp to play from that location

0:00.0

What is a peptide? Like, what makes the difference between a peptide and a supplement?

0:04.7

The definition of a peptide is going to be a chain of amino acids. The FDA at one point decided to

0:11.3

make a quantitative value of any peptide that's greater than 40 amino acids they're going to call

0:17.8

a biologic. Actually, I disagree with that definition. Insulin's

0:21.0

a peptide. All the GLP-1s are peptide. Do you think we're at a place or are we anywhere close to

0:27.0

be able to make peptides orally as bioavailable as the ones you inject? We're sort of there

0:33.0

already. The problem that I see with that is that our bodies are designed to break down proteins

0:38.4

and peptides. So sometimes it's just easier just to inject it than it is to like, you know, try to

0:42.7

stomach it. You almost always have better bioavailability through injection. I mean, with IV,

0:46.9

you're literally putting the drug in the bloodstreams. Are these drugs within a category where people

0:51.6

can just like start and stop whenever they like.

0:54.3

Yeah, so you have that start and stop, and then some people stop and they're fine.

0:57.6

All right, Justin Kirkland, thank you so much for your time today. We really appreciate it.

1:01.0

Yeah, thanks for having me.

1:02.6

Let's just get ready to it. What is a peptide? Like, what makes the difference between a peptide and a supplement?

1:08.3

What's that line that's divided between those two?

1:11.5

Yeah. So technically speaking, the definition of a peptide is going to be a chain of amino acids.

1:18.6

So anytime you have two amino acids connected, that's going to be your peptide.

1:24.5

When peptides get to be much longer and more complex and folded, we typically consider those to be called proteins. And something that we might talk about today is that the FDA at one point, in the past few years, decided to make a quantitative value of any peptide that's greater than 40 amino acids,

1:47.8

they're going to call a biologic.

1:50.2

I don't necessarily, actually, I disagree with that definition in the sense that there are

1:55.3

peptides that can be manufactured by engineering a bacteria to produce them or something

...

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