5 • 716 Ratings
🗓️ 23 July 2020
⏱️ 15 minutes
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0:00.0 | Hey all, welcome back to the real-life pharmacology podcast. I'm your host, pharmacist, Eric Christensen. |
0:06.9 | You can certainly track me down on LinkedIn or at MedEd101.com as well. Just hit the contact button there and shoot me a message. |
0:16.9 | If you have any comments, questions, concerns, this is the Real Life Pharmacology podcast, |
0:22.9 | of course. You can go to real life pharmacology.com and hit the free top 200 study guide |
0:32.0 | in the upper right hand corner of the page. Go ahead and subscribe there and you will get updates when we've got a new podcast |
0:40.3 | available. So definitely go check that out. Get your free 31 page PDF too on the top 200 drugs. |
0:48.6 | Great little refresher and or little study guide if you're preparing for pharmacology or board exam. |
0:56.2 | So go check that out. |
0:58.1 | So let's get into the drug of the day today, and that is simvastatin. |
1:03.6 | So if you've listened to every podcast episode, which I'm guessing most of you probably haven't, |
1:12.9 | but you may remember that we did cover statins in general. And I wanted to branch out and dig a little bit deeper on some |
1:21.7 | of these individual agents because there are subtle differences amongst the statin agents. |
1:30.6 | So with that said, the mechanism of action of simvastatin brand name Zocor is going to be the same. |
1:39.3 | As I covered before, it inhibits HMG COA reductase. |
1:44.4 | If you remember, this is the rate limiting step in basically producing cholesterol. |
1:51.1 | Okay. |
1:51.4 | And that's ultimately going to lower LDL production. |
1:56.4 | And when we do those, when we check our blood for cholesterol levels, hopefully with the use of the |
2:04.2 | medication, those levels will be reduced. But I'll talk a little bit further about monitoring |
2:09.6 | parameters. Use of this medication, lowering cardiovascular risk, lowering cholesterol, |
2:20.3 | and things of that nature, of course. |
2:25.7 | So uniquely, let's talk about some quirks with sympastatin. |
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