4.9 • 806 Ratings
🗓️ 13 February 2020
⏱️ 3 minutes
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0:00.0 | For I use at once as a complete waste. |
0:02.8 | And one thing I should say is I 100% agree with lipolis being a huge factor to your GH being |
0:10.6 | useful or not in a lypolytic context. |
0:13.2 | Like if you're fasted, the effects GH is going to have on fat mobilization in regards to |
0:19.5 | what you're actually burning during your cardio session or your training session if you're fasted versus not fasted it definitely matters like that he's definitely correct on however as far as the amount at once there's a ceiling on lipolysis which he's not accounting for here and it's much lower than most people think and this is why a lot of people are putting unnecessary stress on themselves and wasting money and taking too much GH. |
0:39.6 | As you can see here in the following study, assessing the pharmacokinetics and acute, lipolytic actions of GH. |
0:46.6 | There were significant dose response effects when comparing the incremental area under the curve of both free fatty acids and blood three hydroxybutyrate following 0,1, and |
0:56.6 | three micrograms per kilogram of GH administration, whereas there were no differences between |
1:03.4 | the responses following three and six micrograms per kilogram of GH. |
1:08.4 | So these dosages were administered intravenous. So as far as what |
1:12.6 | milligrams equate to in international units, one milligram of somatropin corresponds to three |
1:18.0 | IU international units of somatropin. You can see this reinforced in the Nordotropin product information |
1:25.9 | pamphlet or their, you know, product information form that they include. |
1:31.4 | So this means that for somebody who weighs 100 kilograms, for example, |
1:35.9 | lipolisus is maxed out at about 300 micrograms of somatropin, which is 0.9. |
1:42.7 | I use of pharma grade GHIV. So we need to math out the corresponding |
1:48.0 | subcutaneous dose based on bioavailability and bioactivity comparison data that we have on |
1:54.2 | humans administered HGH because obviously IV dosages are not representative of, you know, what dosages would be via a far more |
2:04.5 | realistic and tolerable method of administration, which is the subcutaneous route. |
2:10.7 | So in one study, the mean estimated availability of subcutaneous injected HGH was shown to be |
2:16.5 | 63% of HGH administered IV after correcting |
2:21.4 | for the differences in the GH dose. Another study found the availability of subcutaneous injected |
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