5 β’ 716 Ratings
ποΈ 15 August 2024
β±οΈ 17 minutes
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0:00.0 | All right, so getting into the medications today, drug at number 51, the brand name is Lunesta. |
0:07.5 | Generic name is Azopaclone. |
0:11.6 | Its mechanism of action is it binds to and potentiates the effect of gamma receptors leading to a sedative type effect. |
0:20.2 | So, as you can imagine, this medication is |
0:22.9 | classified as a sleeper or a sedative type agent. Again, falls under the classification of a |
0:31.9 | Z drug because the generic name has a Z in it and it's for sleep. So that's a good kind of classification to remember if you're being tested on that. |
0:41.4 | And mechanistically, it works very similar to benzodiazepines. |
0:47.1 | So as you could expect, we are going to have a very, very similar adverse effect profile. |
0:54.9 | So dizziness, confusion, obviously sedation, that's generally what we're trying to do there. |
1:02.8 | Increased risk for falls, particularly in the elderly. |
1:07.2 | Also, you know, associated with most of the sleeping medications, we can have some rare sleep-type |
1:14.4 | side effects. |
1:15.1 | And the Z-drugs are specifically notorious for this. |
1:18.9 | Sleep-walking, sleep-eating, kind of these unique and abnormal sleeping-type behaviors. |
1:27.5 | In addition to that, vivid or bad dreams are possible. |
1:32.6 | This is definitely something I've heard patients report. |
1:36.9 | There is a risk of addiction and dependence with these agents. |
1:41.4 | So they are a controlled substance and they are scheduled for there. |
1:46.8 | So with Lunesta specifically, I keep an eye out for patients who are using this long term. |
1:55.6 | Obviously, like to try to get them off of a controlled substance long term, if at all possible. |
2:02.3 | Do your best limit dose, so minimize that risk for falls and confusion and other kind of |
2:08.6 | collateral damage. And then, of course, making sure that we're tapering periodically or |
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