Hey, all, welcome back to the real-life pharmacology podcast. I'm your host, pharmacist, Derek Christensen.

Thank you so much for listening today. We're going to be continuing on with the top 200 drugs.

We are starting off at 106. Before we get into that, as a reminder, go check out MedEd 101.1.com slash store. We've got a ton of resources there,

pharmacist board certification study materials. We've got things for nursing students. We've got

things for pharmacy technicians. Again, tons of resources there to help you in your journey

of learning medications, helping passport exams.

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All right, so drug number 106 is zolodronic acid.

Brand name of this medication is Zometta and reclassed. It is a bisphosphonate. So if you remember from

previous medications, a bisphosphonate is basically a medication that can be

utilized for osteoporosis. Zolodronic acid can also be used in the hypercalcemia of

malignancy management as well.

So that's an important indication to remember too.

So again, as a reminder, bisphosphonates in general,

they prevent bone resorption by inhibiting osteoclast.

That's definitely a mechanism that I've seen come up on

pharmacology exams and board exams throughout my career. So remembering that bisphosphonates

inhibit osteoclastinates is really, really important. This medication is an IV injection,

typically given over 15 minutes, and it is dosed on an annual basis in the management of osteoporosis, typically.

Adverse effect profile, so with this IV injection or infusion over 15 minutes, flu-like symptoms can happen.

And they can last for, you know, a period of days, maybe even up to a week or two after that injection.

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