4.4 • 859 Ratings
🗓️ 16 April 2025
⏱️ 33 minutes
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In this episode:
Researchers have created a ‘pangenome’ containing the genomes of multiple potato types, something they believe can help make it easier to breed and sequence new varieties. The potato's complicated genetics has made it difficult to sequence the plant's genome, but improvements in technology have allowed the team to combine sequences, allowing then to look for subtle differences in between varieties.
Research Article: Sun et al.
How ancient DNA analysis revealed that unusually bound medieval books are covered in sealskin, and top quarks and their antimatter counterparts are detected after nuclear smash-ups at the Large Hadron Collider.
Research Highlight: Mystery of medieval manuscripts revealed by ancient DNA
Research Highlight: Top quarks spotted at mega-detector could reveal clues to early Universe
Analysis from Nature reveals the 25 highest-cited papers published this century and explores why they are breaking records. We hear about the field that got the highest number of papers on the list, and whether any feature in the all-time top citation list.
News Feature: Exclusive: the most-cited papers of the twenty-first century
News Feature: These are the most-cited research papers of all time
News Feature: Science’s golden oldies: the decades-old research papers still heavily cited today
Re-analysis of a cosmic collision shows evidence of a planet spiralling into its host star, and how shrugging off lighting strikes gives tonka bean trees an evolutionary edge.
Science: Astronomers spot a planetary ‘suicide’
Live Science: Tropical tree in Panama has evolved to kill its 'enemies' with lightning
Vote for How whales sing without drowning, an anatomical mystery solved
Vote for Cancer-busting vaccines are coming: here's how they work
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0:00.0 | nature in an experiment |
0:05.0 | why is blight so far like it sounds so simple they had no idea but now the data's |
0:12.0 | I find this not only refreshing but but at some level astounding nature |
0:20.0 | welcome back to the Nature. |
0:22.2 | Nature. |
0:25.8 | Welcome back to the nature podcast. |
0:29.6 | This week, a potato pan genome. And the most cited research papers of the 21st century. |
0:35.0 | I'm Benjamin Thompson. |
0:36.2 | And I'm Nick Pertr-Chow. |
0:45.3 | Okay. 21st century. I'm Benjamin Thompson and I'm Nick Perchichal. First up on the show, researchers have been creating a collected group of genomes known as a pan genome to understand the genetic diversity of the humble potato. |
0:57.7 | This effort could help in the breeding of new potato varieties, such as those adapted to disease or |
1:03.7 | climate change. Now, potatoes are incredibly flexible. You can boil them, you can mash them, |
1:10.4 | and you can even feed over |
1:11.8 | one billion people with them. But if you want to make a new variety of them, that isn't so easy. |
1:19.2 | So compared to their cultivars, potato is practically difficult because of the tetraploination. |
1:26.5 | This is Sergio Tussaud, a geneticist who's very familiar with the difficulties |
1:31.7 | potatoes and the breeding of their different varieties or cultivars pose. |
1:37.5 | You see, the potato is tetraploid, meaning that instead of having two sets of chromosomes, |
1:47.8 | like you and I do, potatoes have four. |
1:52.5 | So this makes it particularly difficult what is related to breeding programs, right? |
1:57.4 | So you want to introduce new traits or characteristics, then it's very difficult to put it in the four copies of the genome. |
2:00.0 | So that means that the breeding programs in potato has not been very effective |
... |
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