4.1 • 11.9K Ratings
🗓️ 20 April 2020
⏱️ 16 minutes
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0:00.0 | I'm Elise Hugh with today's TED Talks Daily. |
0:06.7 | Laura Dirkovich is an anthropologist, and early into her first pregnancy, she learned a bombshell |
0:12.0 | about her own biology. But she didn't worry too much. Why? Because she understood her own genetic |
0:19.4 | history, she was able to make better decisions about her |
0:22.2 | personal health. Check out how taking an evolutionary perspective could help us all understand the |
0:27.7 | intricacies of human health in this talk from TEDx Tufts in 2019. |
0:35.2 | When I was approximately nine weeks pregnant with my first child, I found out I'm a carrier |
0:40.9 | for a fatal genetic disorder called TASX disease. |
0:45.4 | What this means is that one of the two copies of chromosome number 15 that I have in each |
0:51.5 | of my cells has a genetic mutation. |
0:59.5 | Because I still have one normal copy of this gene, the mutation doesn't affect me. |
1:06.5 | But if a baby inherits this mutation from both parents, if both copies of this particular gene don't function properly, it results in Tasex, an incurable disease that progressively |
1:13.2 | shuts down the central nervous system and causes death by age five. For many pregnant women, |
1:20.6 | this news might produce a full-on panic. But I knew something that helped keep me calm when I |
1:26.3 | heard this bombshell about my own biology. |
1:29.4 | I knew that my husband, whose ancestry isn't Eastern European Jewish like mine, |
1:34.6 | had a very low likelihood of also being a carrier for the TASX mutation. |
1:40.0 | While the frequency of heterozygotes, individuals who have one normal copy of the gene and one mutated |
1:46.0 | copy, is about one out of 27 people among Jews of Ashkenazi descent, like me, in most populations, |
1:54.5 | only one in about 300 people carry the Tasex mutation. |
1:59.6 | Thankfully, it turned out I was right not to worry too much. |
2:02.6 | My husband isn't a carrier, and we now have two beautiful and healthy children. |
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