4.9 • 806 Ratings
🗓️ 19 January 2018
⏱️ 2 minutes
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0:00.0 | So up guys, this is Derek from more plates more dates.com. |
0:03.6 | Today we're going to be talking about can SARMs cause gyna comastia, also known as |
0:08.9 | gyno. |
0:09.6 | So one of the very common questions I get asked is about SARMs and high estrogen side |
0:16.7 | effects. |
0:17.2 | So one of the biggest myths circulating in the community is that SARMs cannot cause |
0:23.2 | estrogen-related side effects because they don't aromatize directly into estrogen. And if you do |
0:28.5 | experience high estrogen side effects, then you have fake SARMs or pro-hormone-lase SARMs. But |
0:36.4 | the majority of the time, this couldn't be further from the truth |
0:39.4 | and is simply a misunderstanding of the mechanism of action of these compounds. |
0:45.2 | So, and how they interact with the androgen receptors in the body. |
0:48.8 | So you have to remember SARMs were developed |
0:51.3 | to have a very high binding affinity to the androgen receptor. |
0:55.5 | So one thing that isn't taken into account very often is that their binding affinity is much |
1:01.1 | higher than most steroids, including the steroids your body naturally produces testosterone |
1:06.4 | and dihydrotestosterone DHD. |
1:08.3 | So when the human bodies, androgen receptors are flooded with SARMs that bind tightly, |
1:14.5 | there are less vacant androgen receptors for the testosterone in your body to bind to, |
1:19.9 | which ultimately can lead to a flooding of unusable, you know, |
1:25.3 | androgens in your body and divert a greater amount of testosterone to convert |
1:30.2 | into estrogen and dh t so in addition the higher your dose of sarms are the more your available |
1:37.5 | testosterone will be diverted towards estrogen and dh t conversion because there are less and less |
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