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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Epoetin Alfa Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 9 July 2020

⏱️ 15 minutes

🧾️ Download transcript

Summary

Epoetin alfa is essential exogenous erythropoetin which can stimulate the production of red blood cells.



It is critical to ensure adequate iron stores when using EPO.



Risks for blood clots, strokes and heart attacks are critical to recognize with the use of epoetin.



Dosage adjustments with epoetin are typically made with respect to the amount of change in hemoglobin. I discuss this further in the podcast.

Transcript

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0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I am your host pharmacist, Eric Christensen.

0:05.6

Thank you so much for listening today. Go check out Real Life Pharmacology.com. Get your free 31 page PDF,

0:14.8

the top 200 drugs. Great little study guide. Great review if you're out in practice.

0:24.7

Really nice, nicely put together on some of the most common clinical pearls, adverse effects, things that you're actually going to see in practice,

0:29.6

as well as things that come up on board exam. So go get that for free, simply an email. We'll get you

0:35.5

that and we'll get you updates when we've got new podcasts available

0:38.8

and new content as well there.

0:41.1

So again, you can do that at real-life pharmacology.com.

0:45.1

All right, drug of the day today is Ipoetan alpha.

0:49.5

Brand name of this medication is epigen, pro kit, reticrit.

0:56.5

This is a medication I've definitely seen used in practice. I would say I've seen maybe less use as time has gone on because we've seen

1:05.5

warnings and different things come out with this medication. So it definitely has to be used wisely and judiciously.

1:13.3

And so hopefully I can teach you some clinical practice pearls

1:16.9

with the use of this medication.

1:20.5

All right, so you'll often hear clinicians talk about ESAs.

1:27.4

So that's erythropoesis stimulating agents.

1:31.9

And there are other medications within this class, but one of those is epaweeton Alpha, or

1:37.3

epigen is probably the most common brand name I here used.

1:41.9

So as the name implies, they stimulate erythropoesis. So essentially the drugs

1:50.3

stimulate the production of red blood cells. The drug causes the release of reticulocytes

1:59.8

from bone marrow. So if you remember reticulocytes are basically

2:04.9

kind of precursors or immature red blood cells that eventually mature to erythrocytes. And long

...

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