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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Fluticasone, Umeclidinium, and Vilanterol Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 23 April 2020

⏱️ 12 minutes

🧾️ Download transcript

Summary

Fluticasone, Umeclidinium, and Vilanterol is a combination medication used in the setting of COPD. I discuss the pharmacology of this agent further in this episode.



Fluticasone is the inhaled corticosteroid portion of the drug while umeclidinium is a LAMA and vilanterol is a LABA medication.



Drug interactions aren't incredibly common or strongly clinically significant, but I discuss some of them with Trelegy Ellipta.



Having a once-daily dose can be advantageous to help improve patient adherence. Fluticasone, umeclidinium, and vilanterol comes as a once-daily combination.

Transcript

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0:00.0

Hey all, welcome back to the real-life pharmacology podcast. I'm your host, Eric Christensen.

0:06.9

If you want to track us down, check us out at real-life pharmacology.com. Definitely take

0:12.8

advantage of that free 30-plus page PDF on the top 200 drugs if you're studying for

0:19.5

pharmacology or just looking to pick up some

0:22.5

clinical practice pearls. Definitely go snag that PDF for free at real art pharmacology.com

0:29.0

and we'll also get you updates as far as when we have new podcasts available.

0:36.1

So the drug I'm going to cover today is a combination product that I am seeing periodically now.

0:44.2

Fluticazone, umacladinium, and volantorol is the combination.

0:50.6

So this is an inhaled medication primarily for the use of COPD.

0:58.3

It's a combination medication, obviously. It's got three different drugs.

1:03.4

So the Fluticazone is an inhaled corticosteroid.

1:07.8

Umaclidinium is a long-acting anticholinergic and volantorol is a long-acting

1:13.9

beta-2 agonist. So one of the big clinical advantages with this medication is its dose once a day

1:26.2

and we've got three medications within it.

1:31.2

Now that can be a good and a bad thing.

1:33.7

Obviously the once daily is a huge advantage for patients.

1:38.4

It's a very convenient thing to use.

1:41.5

You can factor it into your daily routine versus a medication

1:45.8

that, you know, you maybe do two or three times a day. That gets a little bit trickier sometimes

1:51.4

for some patients to follow that regimen. So more doses you add throughout the day, the more and

1:57.7

more likely that you're going to see patients skip doses, missed doses,

2:03.2

forget doses, or whatever the case may be there.

...

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