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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Gentamicin Pharmacology Podcast Episode 311

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 25 January 2024

⏱️ 15 minutes

🧾️ Download transcript

Summary

On this podcast episode, I discuss gentamicin pharmacology, adverse effects, monitoring, drug interactions and much more!



Drug monitoring is critical with gentamicin. Trough and peak concentrations can guide therapy and identify someone at risk of toxicity.



Nephrotoxicity is a major concern with gentamicin. There are numerous nephrotoxic agents that can increase this risk. I discuss them on the podcast.



Ototoxicity is another risk associated with gentamicin. Loop diuretics like furosemide can increase this risk. Learn more on this podcast episode.

Transcript

Click on a timestamp to play from that location

0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

0:05.9

Thank you so much for listening today. As always, go check out real life pharmacology.com.

0:12.1

We've got a free 31-page PDF. It's a great study guide on the top 200 medications.

0:19.7

I lay out some of the most important things

0:21.7

that you're going to need to know for clinical practice,

0:24.0

as well as things that often come up on board exams.

0:27.0

So go check that out.

0:29.0

Great little review or refresher for you there.

0:32.7

All right.

0:33.6

So let's get in the drug of the day today,

0:35.6

and that is gentimicin.

0:38.1

And for purposes of this podcast, I'm going to primarily focus on systemic.

0:44.3

Most of the times we're going to be doing IV administration inside a hospital or in an institutionalized setting, potentially some outpatient IV therapy and stuff like that too.

0:56.5

But that's really going to be my primary focus here.

1:00.0

So primary uses of that injectable gentemycin, usually it's fairly severe infections,

1:08.2

but in situations where maybe we don't have many options or there's tons of resistance or something like that, you may see this medication utilized there too.

1:17.9

So urinary tract infections, meningitis cases, sepsis, in those severe situations, life-threatening situations, it's generally going to be used as

1:31.2

add-on therapy in empiric cases where maybe we can't utilize another agent or we need to

1:39.0

cover certain bacteria. There are a few other uses that are of note, I guess.

1:48.0

One I guess I wanted to mention was gonorrhea.

1:51.4

It is kind of a down-the-line option if patients have intolerances to some of the main

1:57.0

drugs there.

...

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