4.8 • 3.6K Ratings
🗓️ 6 June 2024
⏱️ 12 minutes
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0:00.0 | There are lots of good reasons to try and follow a healthier diet. |
0:05.0 | You lose weight, you feel good, but the main reason, to live a longer, happier, more productive life. |
0:13.0 | Welcome to the Nutrition Facts Podcast. |
0:15.0 | I'm your host, Dr. Michael Greger. |
0:18.0 | Today we look at how to make sense of the disparate results from the four primate studies on caloric restriction and lifespan. |
0:25.4 | Calary restriction and primates to extend lifespan. |
0:28.9 | Will it work? There's only one way to find out. |
0:33.0 | There have been four investigations of calorie restriction and lifespan in non-human |
0:37.6 | primates. |
0:38.6 | The first was published in 2003, an analysis of the mortality of a hundred and seventeen |
0:44.4 | Reese's monkeys followed for about 25 years in a lab, eight of whom had their |
0:48.9 | Purina monkey chow restricted. The average survival of the restricted monkeys was to 32 years of age |
0:56.8 | compared to 25 years for the control monkeys. |
1:00.0 | However, it was more of an observational study since the monkeys weren't randomly assigned. |
1:05.6 | And although in the abstract they talk about the survival advantage and how the |
1:09.4 | ad libidim monkeys, or eat all you want monkeys, had more than twice the risk of death, but they acknowledge |
1:16.0 | deeper into the paper that the difference in death did not reach statistical significance |
1:21.5 | meaning it may very well have been a fluke. |
1:25.2 | That was all we had, though, until results started trickling in from the famous pair of studies |
1:30.2 | that involved randomizing about 200 racist monkeys to caloric restriction or more |
1:35.3 | normal diets, one out of the University of Wisconsin-Madison and another from the National |
1:40.5 | Institute of Aging. The UW study reported the 30% calorie restrictions |
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