Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, Eric Christensen.

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The drug of the day today is Tizanidine.

Brand name of this medication is Xaniflex.

And I will say see it used periodically anyway in geriatrics specifically.

Most often the indication that it's going to be used for is muscle spasms.

And this drug is classified as an alpha-2 adrenergic agonist.

And the way I kind of remember some of the effects and things of that nature is

Tizanidine and Klonidine do have some similarities mechanistically.

Ultimately, as far as its antipsmastic type activity.

It can cause neuronal presynaptic inhibition is basically how it ends up working.

And it helps me, because I see clonidine a little bit more, I think clonidine's a little bit more well known or well

taught, maybe drug, and understanding that it's going to have some similar mechanism, you're going to

have some similar type adverse effects. So side effect profile, I think about blood pressure lowering effect.

But in addition to that, there's also warnings on if patients are taking Tizanidine consistently

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