5 β’ 716 Ratings
ποΈ 9 January 2025
β±οΈ 24 minutes
ποΈ Recording | iTunes | RSS
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0:00.0 | Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen. |
0:05.3 | Thank you so much for listening today. Continuing on, we are on drugs 156 through 160. |
0:13.8 | I also want to remind you guys, top 200 drugs. It's a great study guide, absolutely free PDF, 31 pages at real life pharmacology.com. Simply an email, |
0:23.8 | we'll get you access to that. I've highlighted a few of the most important things that you're |
0:28.8 | likely to see in practice, as well as on board exams, pharmacology exams, and things like that. |
0:34.9 | So go check that out, free resource for you. Simply an email |
0:38.7 | will get you access. All right. Getting into the drugs of the day today, 156, we've got |
0:44.7 | niacin. Brand name is Nyaspan. This drug's fallen out of favor a little bit over time here. |
0:53.2 | It's also known as vitamin B3, and mechanistically, |
0:59.0 | where this is used for therapeutic purposes other than potentially nutritional deficiency, |
1:06.5 | it can help lower cholesterol, and it does this by inhibiting triglyceride formation. |
1:13.5 | It's not totally understood how that works. |
1:17.2 | But if you've got a patient that's kind of resistant to other therapies, |
1:21.6 | or it's not working or it's not tolerable, let's say like a phenofibrate, for example, |
1:26.4 | is a commonly used medication for very high triglycerides. |
1:29.8 | If that's not working, |
1:31.3 | niacin may be a potential option. |
1:33.3 | And the dosage form, Niaspan, |
1:37.2 | is an extended release dosage form |
1:40.4 | that may be a little bit better tolerated. |
1:44.8 | In addition to those effects on triglycerides, it may help increase HDL. |
1:51.3 | That's considered the good cholesterol, where LDL is the bad cholesterol. |
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