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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Top 200 Drugs Podcast – Medications 151-155

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 2 January 2025

⏱️ 23 minutes

🧾️ Download transcript

Summary

Today’s sponsor is Freed AI! Freed’s AI medical scribe listens, transcribes, and writes notes for you. Over 15,000 healthcare professionals use Freed and you should too! Learn more here!



On this episode of the Top 200 Drugs Podcast, I cover medications 151-155. This podcast includes; cefuroxime, ketoconazole, pregabalin, esomeprazole, and ipratropium/albuterol.



Cefuroxime is a 2nd generation cephalosporin that has a very similar bacterial coverage profile to amoxicillin. It has significant gram positive coverage.



Ketoconazole is an azole antifungal medication. It is well known for causing hepatotoxicity as well as interactions via CYP3A4.



Pregabalin has a lot of similarities with gabapentin. It can be used fo various pain syndromes such as neuropathy and fibromyalgia.



Esomeprazole is a PPI and has a similar profile to omeprazole. It inhibits CYP2C19 and has a few notable interactions that I cover in this episode.



Ipratropium and albuterol is a combination of a short acting anticholinergic and short acting beta agonist.

Transcript

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0:00.0

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0:50.6

Hey, all, welcome back to the Real Life Pharm pharmacology podcast. I'm your host pharmacist,

0:54.8

Eric Christensen. Thank you so much for listening today. We are moving on with the top

1:00.0

200 drugs. We're already at drug 151. So we'll have 151 to 155 covered today. That first

1:09.3

medication is Seperoxime.

1:11.9

Brand name is Seftin.

1:14.9

Remember, there are multiple generations of cephalosporins.

1:19.0

Typically with cephalosporins, the earlier the generation, first generation, second generation,

1:24.4

the more coverage you have towards specifically gram positive bacteria,

1:30.0

classic examples being Staphylococcus, streptococcus. And that's true of

1:35.2

Cephyroxene for the most part. It tends to have much more gram-positive coverage. It is a second-generation cephalosporin.

1:46.0

Usages, you might see this medication for strep throat, otitis media, pneumonia.

1:55.0

It has activity against more accelerates catarralis, more commonly referred to as MCAT, also as H-flu activity, and then

2:06.0

Strep and staff coverage as well. Typically, it's not going to cover MRSA or it's not going to

2:12.2

be beneficial for that. So that is a potential downside there where you'd have to look towards an alternative agent that does have that coverage.

...

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