Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host pharmacist, Eric Christensen.

Thank you so much for listening today. Go check out Real Life Pharmacology.com. Get your free 31 page

PDF on the top 200 drugs. A great little study grad, great refresher. If you've been out in practice for a little while,

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and some of the most important things that you're going to see on pharmacology exams throughout school

and maybe board exams throughout your career as well.

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And we also get you updates when we've got other content available. All right. So we are continuing on our list of the top

200 drugs and we've got numbers 31 through 35 today. The first drug is ethanol estradial

and drosparinone.

This is an estrogen progestin combination oral contraceptive.

Sometimes you'll see the generic kind of abbreviation OCs for oral contraceptives.

Sometimes you'll see COCs for more specific, more for combined oral contraceptives.

So keep those abbreviations in mind there.

Brand name of this medication, if I didn't mention it, is Yaz.

Mechanism of Action, how these combined oral contraceptives work,

they block ovulation by negative feedback on the hypothalamus.

The hypothalamus, then in turn, works with the pituitary anterior, anterior pituitary, and that reduces FSAH and LH secretion.

So FSH is follicle stimulating hormone and LH is lutinizing hormone. And by reducing that secretion of

those two, that prevents ovulation, which is obviously what we're trying to do with oral

contraceptives and maybe even a more generic term birth control.

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