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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Top 200 Drugs Podcast – Medications 126-130

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5 β€’ 716 Ratings

πŸ—“οΈ 28 November 2024

⏱️ 24 minutes

🧾️ Download transcript

Summary

In this episode of the Top 200 Drugs Podcast, we cover medications 126-130.



Trastuzumab is a monoclonal antibody that can be used for breast cancer that expresses the HER2 protein.



Atripla is an HIV medication that contains three separate medications that are beneficial in reducing viral load.



Rivaroxaban is an anticoagulant that may be commonly used in the management of stroke and deep vein thrombosis.



Fioricet is a combination of three medications. Butalbital, acetaminophen, and caffeine are the three ingredients in this medication.



Insulin detemir is a long-acting insulin analog that lowers blood sugar. This medication is used to target fasting blood sugars.

Transcript

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0:00.0

Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host pharmacist, Eric Christensen.

0:07.7

Thank you so much for listening today and a very special thank you as I'm releasing this on Thanksgiving Day.

0:15.0

So thank you for all the kind words, support, words of encouragement, purchases, books, everything that you guys have done.

0:23.7

I'm greatly appreciative of all that. It allows me to continue to do this, which I certainly enjoy

0:29.5

doing. So with that said, go take advantage of the free PDF at real life pharmacology.com.

0:37.7

It's a 31-page PDF on the top 200 drugs.

0:40.3

Simply an email.

0:41.4

We'll get you access to that.

0:43.9

And I thank you so much again for the support of the podcast.

0:49.1

With that public service message completed,

0:52.1

let's get into the drugs that I'm talking about today. We've got

0:55.0

numbers 126 through 130. First medication is trastusimab. Brand name is Herceptin. And if you can

1:03.9

remember that first part of that brand name, Her, H-E-R, that is a really important thing to remember if you're

1:10.0

taking pharmacology exams,

1:12.6

specifically on oncology or maybe a final exam or board exam. That H-E-A part indicates part of its

1:21.6

mechanism of action. So classification-wise, Tresytusimab is a monoclonal antibody.

1:28.6

Remember that ending MAB MAB, classified as an oncology agent,

1:33.6

or you may hear it referred to as an anti-neoplastic agent as well.

1:38.7

Tristhumab is a monoclonal antibody, which binds to the extracellular domain of the human

1:45.9

epidermal growth factor receptor 2. That's where the HER2 classification or mechanism

1:54.5

goes to talk about. So ultimately, it mediates antibody dependent cellular cytotoxicity by blocking

2:05.7

proliferation of cells, tumor cells, cancer cells, which overexpress this protein,

...

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