5 β’ 716 Ratings
ποΈ 28 November 2024
β±οΈ 24 minutes
ποΈ Recording | iTunes | RSS
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0:00.0 | Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host pharmacist, Eric Christensen. |
0:07.7 | Thank you so much for listening today and a very special thank you as I'm releasing this on Thanksgiving Day. |
0:15.0 | So thank you for all the kind words, support, words of encouragement, purchases, books, everything that you guys have done. |
0:23.7 | I'm greatly appreciative of all that. It allows me to continue to do this, which I certainly enjoy |
0:29.5 | doing. So with that said, go take advantage of the free PDF at real life pharmacology.com. |
0:37.7 | It's a 31-page PDF on the top 200 drugs. |
0:40.3 | Simply an email. |
0:41.4 | We'll get you access to that. |
0:43.9 | And I thank you so much again for the support of the podcast. |
0:49.1 | With that public service message completed, |
0:52.1 | let's get into the drugs that I'm talking about today. We've got |
0:55.0 | numbers 126 through 130. First medication is trastusimab. Brand name is Herceptin. And if you can |
1:03.9 | remember that first part of that brand name, Her, H-E-R, that is a really important thing to remember if you're |
1:10.0 | taking pharmacology exams, |
1:12.6 | specifically on oncology or maybe a final exam or board exam. That H-E-A part indicates part of its |
1:21.6 | mechanism of action. So classification-wise, Tresytusimab is a monoclonal antibody. |
1:28.6 | Remember that ending MAB MAB, classified as an oncology agent, |
1:33.6 | or you may hear it referred to as an anti-neoplastic agent as well. |
1:38.7 | Tristhumab is a monoclonal antibody, which binds to the extracellular domain of the human |
1:45.9 | epidermal growth factor receptor 2. That's where the HER2 classification or mechanism |
1:54.5 | goes to talk about. So ultimately, it mediates antibody dependent cellular cytotoxicity by blocking |
2:05.7 | proliferation of cells, tumor cells, cancer cells, which overexpress this protein, |
... |
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