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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Top 200 Drugs Podcast – Medications 91-95

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5 β€’ 716 Ratings

πŸ—“οΈ 10 October 2024

⏱️ 24 minutes

🧾️ Download transcript

Summary

On this episode of the Real Life Pharmacology Podcast, I cover 5 more medications of the top 200.



Fenofibrate is a medication used primarily to reduce triglycerides. This medication differs from statins which tend to focus on LDL management.



Doxazosin is an alpha-blocker. The primary indications of doxazosin are hypertension and BPH.



Naproxen is an NSAID. Of all the NSAIDs, naproxen is one of the lower-risk agents with regard to cardiovascular risk.



Spironolactone is an aldosterone antagonist and also classified as a potassium sparing diuretic.



Memantine is an NMDA antagonist that is indicated for the management of Alzheimer's dementia.





If you are looking for study materials and our list of popular Amazon books, check out meded101.com/store!

Transcript

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0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Derek Christensen.

0:05.5

Thank you so much for listening today. As always, go check out Real Life Pharmacology.com. I've got all

0:11.7

these medications more in-depth. If you're looking for a specific review on a medication, the drugs today

0:20.3

are going to be phenofibrate, doxazosin, neproxin,

0:26.0

spirulactone, and the last one we'll cover is memmintine. So again, I've tackled all these

0:33.7

medications individually and much longer, more detailed podcasts. So definitely go to

0:39.1

real life pharmacology.com, hit the podcast tab, and there should be a search bar on there where

0:44.0

you can search a specific medication and go back and listen to them in more detail. So take

0:50.4

advantage of that while you're at real life pharmacology.com. Definitely go check out the top

0:55.9

200 medications PDF. It's a 31 page PDF on some of the most important things you're going to see in

1:01.6

practice as well as show up on your pharmacology and board exam. So definitely a no-brainer

1:07.4

to have for any healthcare professional or any aspiring healthcare professional.

1:13.5

All right, let's get into the medications today. We've got phenofibrate.

1:18.4

Brand name of this medication is tricor. There's a bunch of different brand name medications for this.

1:26.3

Trichore, lofibra, phenoglide, those are probably three of the more common ones that I've seen

1:32.9

utilized.

1:34.6

It is a fibrate derivative.

1:38.6

It's a medication used to lower cholesterol.

1:42.5

And mechanistically, its classification is a P. PAR agonist.

1:48.5

So what does that mean?

1:50.5

Phenofibrate is a paroxysome proliferator-activated receptor alpha agonist.

1:58.8

And that activation of P-par.R. Alpha increases lipolysis and ultimately the elimination of triglyceride rich particles from the plasma.

...

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