Top 200 Drugs Podcast – Medications 96-100

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5 • 716 Ratings

🗓️ 17 October 2024

⏱️ 22 minutes

🔗️ Recording | iTunes | RSS

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Summary

We have finally reached 100 of the top 200 drugs podcasts!

On this episode, we tackle methadone. This is a complex opioid used for opioid use disorder and may also be used for pain.

Enalapril is an ACE inhibitor that is used for hypertension. Cough and hyperkalemia are two major adverse effects to remember.

Oseltamivir is a neuraminidase inhibitor. In patients with poor renal function, we need to make sure to adjust the dose accordingly.

Ropinirole is a dopamine agonist. This medication is primarily used for restless leg syndrome but is also indicated for Parkinson's disease.

Penicillin VK is the original penicillin antibiotic. Common indications of this medication are strep throat, skin and soft tissue infections, and syphilis.

Transcript

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0:00.0	Hey, all, welcome back to the Real Life Pharmacology podcast.
0:03.3	I'm your host, pharmacist, Eric Christensen, and I thank you so much for listening today.
0:07.8	Go check out Real Life Pharmacology.com.
0:10.4	We get your free 31-page PDF on the top 200 drugs.
0:15.2	No-brainer to have.
0:16.4	Simply an email, we'll get you access to that.
0:18.7	We'll also get you update when we've got new podcast episodes
0:22.6	and other content available too. So go do that at real-life pharmacology.com. We are continuing on
0:31.1	with the top 200 drugs today, and we are on number 96. This medication is methadone. Brand name is methadose.
0:42.3	And classification, it is an opioid analgesic. I will say in practice, I typically don't use,
0:51.6	see this medication used terribly often for pain management. I would say in
0:55.8	patients I see it more often used in opioid use disorder. This medication helps reduce withdrawal
1:04.0	symptoms and cravings, obviously associated with opioid use disorder there. So how does it work mechanistically? It binds to
1:13.8	opioid receptors in the central nervous system. It is a full opioid agonist that is slightly
1:22.4	different from, let's say, buprenorphine in opioid use disorder, which is a partial opioid agonist.
1:30.9	So there is a little bit of difference there.
1:34.5	As far as boxed warnings, there are a bunch on this medication.
1:40.9	Obviously, being a full opioid agonist, we've got the risk for addiction abuse and misuse potential.
1:48.5	There's also various dosage forms, particularly in relation to concentrations and liquids.
1:57.3	So we've got to be extremely careful with that.
2:00.9	If you give patients prescribed, dispense the wrong concentration, and you tell them to take a set amount of volume, that could definitely lead to a situation where we give an inappropriately high or excessive dose, obviously
2:19.8	unintentionally or in error.
	...

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