Hey all, welcome back to the Real Life Pharmacology podcast.

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I am your host, Eric Christensen.

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All right, with that, let's get into the drug of the day, and that is going to be calcium acetate.

Brand name of this medication is Foslo, and this drug is a phosphate binder.

And so when I think about this, okay, why would we need a phosphate binder?

Essentially, this drug, through its mechanism, binds up phosphorus in the gut

and prevents absorption of phosphorus into systemic circulation.

And this accumulation of phosphorus is generally a problem in patients with

chronic kidney disease. So if you remember, the kidney is the filter of the body. It helps

regulate electrolyte levels and phosphorus is certainly one of those things.

So in KD, we can get hyperphosphatemia, and from that we may need to reduce the risk from some of those complications of hyperphosphatemia by giving a phosphate binder.

Okay, very, very important to, I think,

remember that background and why we would potentially

need a phosphate binder.

Now, this binds phosphate in the gut.

What does that mean as far as administration? So very important to remember to administer this drug

with food or meals. Because we're binding phosphate in the gut. If we're not eating at the time that we're administering this drug,

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