Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, Eric Christensen,

pharmacist. Thanks so much for listening today, and I hope you pick up some practice pearls.

I do want to remind you of the website, real life pharmacology.com. You can go snag your free 31 page PDF of the top 200 drugs.

So definitely a resource that I put together based upon my experiences of taking pharmacology exams, board exams,

and help highlight really important clinical practice pearls,

as well as pharmacology pearls or things you might be tested on

throughout your career or in taking board exams.

So go snag that for free, simply for signing up to follow the podcast.

All right, so let's get into the drug of the day today, and that is syldenafil.

Very common, joked about whatever the case may be, a drug.

Viagra is the brand name of this medication.

But there is also Rivadio, which is a same drug, sylidaphyl, but it goes under that brand name, and it can be used for pulmonary

arterial hypertension. So that is something I have seen in clinical practice a few times. I would say

it's not incredibly common, but if you see somebody taking sylidinifil, usually it's 20 milligrams three times a day

as far as the standard dosing. They are likely not taking that for the most commonly used

indication of erectile dysfunction. Okay. So I'm not going to talk a ton about pulmonary arterial

hypertension, but I do want you to be aware if you see, hey, what the heck is this?

Sildenafil three times a day. That might be the indication there that it's being used for.

Or at least that's the most common I've seen

when you see a dose like that. All right, so dosing for erectile dysfunction, this is typically

going to be in the range of 25 to 100 milligrams, and remember mechanistically how this drug works. It is classified as a

PDE5 inhibitor. What the heck is a PDE5 inhibitor? PDE stands for phosphodiasterase,

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